Unlocking The Metabolic Bottlenecks for Optimal Energy and Health

Your Adrenal Fix With Dr Joel Rosen

Dr. Joel Rosen: All right. Hello everyone and welcome back to another edition of your adrenal fix where we teach exhausted and burnt-out adults the truth about their health so that they can get their health back quickly. Really excited to meet with a colleague.

Sean is who we are going to be talking about metabolic bottlenecking and thyroid and adrenals. Sean is an avid researcher, he is constantly in pursuit of deeper ways of looking at disease and chronic illness through the lenses of biology, biochemistry, genetics, epigenetics, and physiology, he has been dubbed the meta-medic metabolic detective of integrative health, oftentimes, he will be the last person to be seen, I can definitely identify with that after the people have exhausted every other therapy, I could go on and on. But Shawn, I really want to just get into the meat and potatoes. So thank you so much for being here today.

Shawn Bean: And Joel, it’s complete honor being with you, because I’ve followed you for many, many years through my own journey. And a lot of your information has been Paradine and getting me to where I am today. In regards to back in the day, you were the adrenal guy, but we all know now that that whole methodology has changed. And what more of the box thinkers were more of the technicians, you know, the people that put you on the diagnostics on the car, and, you know, the people see the big picture, okay, I refer to this as the 40,000-foot view. Okay, it’s like being up the airplane and looking down, rather than, you know like many people are a specialist, you and I are specialists in being generalists. We’re generalized specialists. Okay. So that’s probably the easiest way I explain myself what do you do? I’m, I’m a specialist in media journalism.

Dr. Joel Rosen: Right. Awesome. Well, listen, I mean, that’s very flattering to know and I appreciate the kind words so I always like to know a little bit about you and I do know some somewhat of your personal story. But for the listeners that may not know, let’s talk about how you became the generalist. That’s what you do.

Shawn Bean: About 20 years ago, I was a natural bodybuilder. To make a long story short, we started the ordered alteration and circadian pattern. I read an article where bodybuilders were getting up at like three o’clock in the morning, you can go back to bed because I’m making no more keep you in protein synthesis. You know, you know, we had a saying that you had to eat every two hours or go catabolic. We know that to be a bunch of nonsense right now. Okay, there are a lot of myths out there that we had no idea about that were disproven. So what happened was, I started getting up at three o’clock in the morning, eating my meal. I read that article from Jay Cutler, who eats like 12 times a day, and I was eating about 10 times a day.

And my whole life revolved around feeding myself. I mean, the number of calories I was eating, I was probably around five 600 grams of protein, 400 grams of carbs, and probably about 135 grams of fat to maintain my 225 pounds, you know, four to 5% body fat composition. Because being a mezzo month, we had to eat calories because I had a fast metabolism.

And I rarely ever did cardio. So what happened there was because of the circadian pattern, I started to have sleep disturbances, I started having museological dysfunctions, and there are warning signs before I even went into contest time. When everyone get done contest, we went decided to have sushi. So being stressed, my immune system was compromised, we were at the sushi bar for about five hours, and I think I put on between 15 and 20 pounds of water weight in that timeframe because, after the contest, you get done, you can literally see yourself growing. You know, it was insane, because of water retention.

And then I started to feel icky afterwards and like and then I started out with mountain direction problems. I went to the doc you know, the whole story, go Doctor GI doctor, nothing wrong, you know, it’s like you got a guy coming in your office now that was like 185 pounds, and then, you know, six weeks later at 240 pounds, you know, the first thing out of the mouth of steroids. Like dude, I hadn’t touched that stuff in years prior for this stuff happens so we can go down that rabbit hole. Okay, and they always want to so I walked into the doctor’s office, and they text my testosterone came back 35 to 35 total, which now we know is basically what is called unit which is basically castration level. No no and explanation. So he gave me like five milligrams of Androgel, which we knew was a total joke, but did nothing. So I started to look at my labs, and I started to know the alkaline phosphatase was low.

I brought this to his attention. He didn’t recognize it. I started to notice my thyroid was off even though it was in a normal range. But you know, the basic stuff that we know now we’re like, Well, this is what’s going on, but back then they had no clue. So fast forward. I had gi problems and then once that happened, I moved into a house with mold in it and then I About a month after moving into the house and mold, I suspected a parasite, and actually two years later I found out the place I ate sushi got closed down by the health board for preparation of food, so I was correct about that. But then I went into a house with mold as a chaperone to a person that had.

He was cerebral palsy. My mom started cleaning the house you didn’t tell me 15 years later, by the way, that there was black mold there. So about a month in I woke up with total amnesia. I didn’t know who I was stuttering slobbering, I was a stranger in a strange land. And that’s when my whole life changed. And we started down these rabbit holes, the doctors, you know, your Oh, your, your, you know, they put you on thyroid medicine. And next thing you know, it’s like, Oh, your thyroid levels are beautiful, and you still feel like crap.

And here I was, you know, I had lost over 90 pounds of lean muscle tissue and even eaten a lot of calories. So it was major malabsorption issues going on? So we went down that rabbit hole. Then they tested my adrenals. The nurse said I don’t know how you’re walking around and my total, my total cortisol levels were at my total cortisol levels were at two on the serum. So therefore I was clinically called Addison’s borderline, Addison’s, but it wasn’t able to do anything. So in that scenario, what happened was is then I went through, and I’m like, Doc, find out what I’m deficient in and put it back in.

Because of the malabsorption issue and that was what I originally started with anyway, in the first place. Because that threw me off because I knew I was deficient in things, everything. You know, it wasn’t absorbing, like I said, I lost. They said I wasn’t as big as I was, I would have been dead. Because I went from 235 pounds at a low percent body fat down to 165 pounds, I liked 14% body fat and less than nine months. So there were a lot of things going on there. So this led into another and this led me down the rabbit hole of heavy metals. I think the biggest thing that helped me was what was known as the PK protocol. And the PK protocol was the phospholipid IVs with the methyl p 12. And the methyl Foley together helped out tremendously. Within six weeks, I had gained most of my strength back, getting back into the normal swing of things.

I walked back into the gym. You know, six weeks later, they thought I had AIDS and here I was back almost some factors on my own strength. Now that led into I was doing really good always back on things. And then I hit fluoroquinolones. Because I was going into my gut, I knew my gut was still off. So I decided to have a parasite test parasite test came back, the parasite test came back with an organism. The drug they recommend it was Joe, Joe myosin, I went to the pharmacist, and they gave me a drug, they gave me Levaquin instead because it was a replacement for GM myosin. And then I took three days of that I felt like my wrist, I felt like it was going to muscles right off.

And that’s when my GI tract, just like, never healed. And after that, then it just started into like one episode of mold right after another, making me more susceptible. And then, just within the past four years, I got a bad mold hit and I had to go through it all again. But my knowledge base was much stronger. But the difference was is we did not have electromagnetic fields 20 years ago. So the electromagnetic fields made the biggest impact on my recovery. And when we moved out of the house of mold, which was great, I felt good, but the thing is we moved into a condo, which was basically right by the, you know, with 35 WiFis going, and here I was trying to get, you know, push my way through, and then we had a gas stove. So you had the overload of the phenol pathway going and the overload of the phenol pathway.

I started noticing little white spots coming up. And we’re starting to see this more and people have coded to, we’re starting to see these little white dots come up with no known explanation. Upon clinical research, I found an article showing that they were actually phenols coming out through your skin as a result of the inability to break it down, I do have a phenol sulfotransferase issue going on, which I had to do to salt to one multiple salt 21 genes. So as you can see the patterns going on. So this is where I’m at today, recovering from another mold hit and I wax and wane when I get a mold hit what happens is it hits my dopamine receptors if my acetylcholine receptors, I can go from the Parkinsonian to the end Jean Mesquita is my, I can never pronounce that word. But you go into acetylcholine deficiency.

So there are some times where, you know, I might wake up stuttering, I may have plus have Asperger’s, I noticed that the mold making my Asperger’s symptoms 10 times worse. I’ll go into a done state, I’ll go into a locked up syndrome state as they would call it, I will go into.

alright, but Okay, I’ll go into the lock them syndrome makes relationships difficult because of mutations. So you see a lot of people that have, like mold, toxicities, and a lot of cases that I’m sure you worked on, and I worked on and many practitioners work on. When you get that mold taken care of a lot of the Asperger’s, a lot of their autistic symptoms go away. And we do see that a lot. And there have been clinical studies showing that Dr. Andrew Campbell, who runs who’s the editor and Director of Medical Director of my micro Labs has seen and documented this multiple times when you address the underlying factor, which is the mycotoxins and the mold.

A lot of these Lyme symptoms and mess and all these other quote, labels get better. And I can attest to that. Because when I do address my metabolic pathways that are associated with the mycotoxins, specific ones, I have glial toxins, and I haven’t done that explained, when I look into the chemical research of what they do, Don mimics celiac. And I’ve been basically living as a celiac and also cystic fibrosis for many, many years because, on my organic acid test, I always kept seeing the elevated of 10 empirics.

And often we see 10 to pure chi, the funny thing is, is I always tell people, I always tell my clients, I said, I bet your sh VG is high, they come back, they’re like, how do you know, I said, You’re a pure chi, that’s using indication that there’s damage to liver on your phase one and phase two. And that usually means your sulfation pathways are off.

And as you know, I’m a specialist in hormones and endocrine systems in regards to a lot of the protocols out there with male hormones actually originated from my findings that were taking, you know, my other doctors because I was not a medical doctor. And as a current trend that we’re seeing, and one of the things was is I was always the one when you look on my you know, on my Facebook, I’m always talking about sh PG, the clinical relevance of it, why is it so high?

There have been very few cases and I’ve been one of them that have actually been able to lower it from high back down to my normal. And I believe that one of the reasons was that I was I was having protein malabsorption. And protein malabsorption was also coming from the dawn. Because what happens is protein malabsorption. Don will mimic celiac, which will shorten your villi. When you shorten your bill what happens is you’ll develop protein synthesis issues. So the thing that I did was I looked at the clinical research and how can I increase my protein synthesis, despite using digestive enzymes and HCl and bitters and yatta yatta yatta, which did nothing. Okay, for mass HPG.

So the two things I found that worked for Heb shot was number one wasn’t treating the mold. Number two, it was actually the things that I did there. I did two things. The only thing I could figure out as I started was glutathione injections because transdermally I can’t transdermal or injections are the only two things that work because I’ve tried every liposomal under the sun. People with gallbladder issues people with mimicking cystic fibrosis, they don’t absorb lipo slumps, because there are gallbladder issues, okay? So I only take that chance no more. And it was the same thing with a lot of my supplements.

So I either go transdermally or injected I, you know, nasal, up the rear, whatever I can do to get it in. Okay. And during the injections was a huge asset, because I could do the injections three times a week I made sure I could recycle it. Now the only thing you have to watch with glutathione injections is you have to make sure that you don’t have high Gliotoxin because in clinical research if you have the glial toxin, there’s a potential chance that the glutathione can potentially feed itself because it does work out the disulfide pathway that it did find out it’s a complex sequence of events, but I actually had mapped out on different clinical research with that, that I could potentially share with you in studies, but using the glutathione in my case, in a few other cases work wonderfully.

But the problem was is after three or four months, we started to get negative effects from it. And we suspected that it was helping the inflammation in the glial toxins. But on the other end, what it was doing was also potentially feeding it. And in one case where I had, we did glutathione acetylcholine, uh, we use the S acetyl glutathione. And what happened was, we had this kid back to fully functional, and I believe he grew like three to four inches within six months. It was insane.

But it was like his father’s back, you know, my son’s back, but then he fell down again. Okay. And guess what we found inside his mycotoxin test, glial toxin. So, proper analysis of the labs is crucial, because you have to know what pathways are being affected. Gliotoxin also works on local trains, the before pathway, you know, very similar to aspirin. So if you have a slight problem, salicylates will inhibit the local train response from that pathway. So, giving things like fish oils is counterproductive in those scenarios.

So, so anything that shuts that down, you want to be careful off because you want to stimulate it, because that look, what happens is the glial toxin shuts that pathway down. And when it shuts down, it can’t respond to other infections. So your immune system gets knocked out. As a response to that. So different organisms. The fungus is the gun, the mycotoxin of the bullet, okay, and the thing is, is when mycotoxins. It doesn’t matter whether it’s Candida, fungal yeast, or whatever the end products are usually summered alcohol.

That’s why when I start treating my client I’m treating but when advising my clients and recommending its recommendations, they are based upon three different criteria that I’m starting to find out. Allegra, which is an alcohol, number two alcohol or nonalcoholic fatty liver, and three traumatic brain injury. When you start to address those things from those angles, and reverse engineer, the microbiome, the endocrine system, the nutritional deficiencies, the environmental toxins, and the brain, then you’ll start to see how everything connects together. And it’s this connection that the majority of practitioners are missing because they are a specialist.

Go to a mold specialist. They focus on mold, they give you a Schumacher protocol. Say Schumaker protocol is good for some people. But if you have low cholesterol, you can’t do core styling. Why do you have low cholesterol because Aspergillus Penicillium is guess what? A statin. So basically, in my line in my biochemistry, I have been living with a person that has been poisoned by statins, poisoned by fluoroquinolones, an alcoholic living with cystic fibrosis, and also a celiac altogether. So what I did was I looked at the pathologies of those conditions, and reverse engineer them through the metabolic pathways and the gene expressions, to better understand a lot of the chronic illnesses that we deal with, which actually has a very similarity to autism.

Because I’ve got into this study in autism, because of somebody on the, you know, somebody on the online, said, Have you ever thought about you being autistic? Well, that makes sense. Because, you know, 35 You know, when we were growing up, okay, we had people you’re shy. Okay, shy, was formerly depression. I had classical signs of Asperger’s back then. I was extremely highly intelligent but had dyslexia. I could count do mathematical explanations and never carry a book to school. I would fall asleep in class wake up, answer the question, and go back to sleep. And I even got to the point to where the teachers thought I was cheating.

Because I never did I rarely did my homework. I didn’t do things to completion. But I fulfilled all the criteria. And I was one of the few students that has ever gone from the bottom end of the learning class. Because they always put you in categories based upon, you know, reading, because you’re always reading low, then you’re gonna be science low and this low. Well, I was the only student in my class that jumped from low science up to the gifted class. And I was outscoring the valid, I was actually out and doing the valedictorians.

Because of my science background. And because what happened was we had the SATs back then. And the SATs were an indication of how smart you are. Well, that’s not so true. Because I had a learning disability, I was scoring 700 on the SATs, because of the time strain. And the problem was how the questions were asked was, I was trying to take something simple and turn it into something that was rocket science. And I was never my brain didn’t work that way.

So one of the gifts that I have as a clinician is I have this holographic viewpoint where I can take a case, look at the labs, break them down scientifically in metabolic pathways, the gene expressions, and then actually formulate the regiment based upon all the criteria but also the contraindications based upon the hit hidden factors. Like for example, it’s like people are taking questions they don’t understand the question. downstream, the alcohol dehydrogenase pathway actually backlogs Lindsey NAT’s pathway.

So if you have fatty liver and you have an alcohol or mycotoxins the alcohol dehydrogenase pathway is going to get overloaded. And then at pathway dependent on sisal transferees pathway is going to get overloaded. So that’s where your B five B, one molybdenum comes in. But if you get questions persistence inhibits that.

So, therefore, you’re going to have problems with phenol issues. Solve late issues and that phenol sulfotransferase pathway is gonna get overloaded again, which a lot of people have. And you can look at the phenol sulfotransferase pathway by just looking at the Dutch test, just looking at the organic acid test, they cross-reference each other. So if you see number 61, hi, and number 10. Hi. And then you see on the Dutch test, you see the DHEA, say at 12 o’clock, and you see the DHEA s at nine o’clock. That’s a sulfation pathway problem.

And then what you do is you go back on and look at your genetics and boom, there it is sought to a one-two a to read. So what I do is I’ve learned to number one, that genetics is a map. It’s not absolutely. So I know that sounds against the current trend, but that’s what I do. I’m a renegade, I go against the current trend. I don’t look at genetics anymore. I don’t need you. As a clinician, I’ve learned to reverse engineer this to know exactly what genes are expressing based on symptoms based on lab test results. The organic acid test is over 16 different gene expressions I figured out. And then when you’re looking at erotic acid, that orotic Acid is only ammonia if it’s high. And second of all, if it’s low, it’s actually possible to clean the indication of Pemt gene expression.

So when a female comes in, I see low erotic acid on the organic acid test, which is number 60. I’m like, I bet your estrogen levels are low. And then boom, what do we do? We do an estrogen test. There they are. So, therefore, they’re, you know, at a person who has had a hysterectomy. 15 years ago, her doctor only gave her progesterone. She gave me 150 pounds. We did the organic acid test. We saw her levels were low. I said let me add you know, she’s like there’s no medical doctor around here. I said listen, I’ll find you one. If I don’t find you one, there are things that we can do over the counter. So we used an over-the-counter Astra da just to balance it out something you’re a professional word is and this is balanced about okay, because their philosophy is Oh, you have one ovary. Okay. She had a partial rectory.

Oh, yeah. Partial of your party your ovary is perfectly fine. Okay, I’m sure you hear it all the time. In that scenario, what did we do? We gave her a little bit of estrogen. She slept for the first time in 15 years. After six weeks she had lost 1520 Paris. She got Shawn I want to fly up there and give you a hug and guess I said to.

Dr. Joel Rosen: Say a little estrogen started interrupting like five milligrams. What are you talking about?

Shawn Bean: Um, what we did was as I usually run two points, I usually run between one to two of biased, because Astra dial will break down into the different metabolites. And this is where I like, get, like, ruffled because they’ll come in on estradiol. When we measure their metabolic pathways, they’re going toward the four hydroxy Ester, and they’re going to the two hydroxy yesterday, and they’re going down the different pathways when they also have a history of breast or union rearing cancer.

Okay, so the other pathways are not being addressed. So what I tend to do is, is I want to look not just upstream-downstream, but science stream, just to make sure the recommendations are adequate for their person. Because, you know, here you are, you know, I had one case of a woman who had advanced cancer, she went to a plant material based diet, okay, what happened was, she went to alkaline. So when she went to alkaline her body started producing acid against it.

So the tumor started growing even faster, because she went on a plant tertian diet, only eating plants in her cat. In her case, it was counterproductive. I said, Listen, we need to put more acid in your system because your body is trying to produce acids to offset the alkalinity. You know, we did and guess what happened? Has the cancer tumor slowed? Because just because it’s in the literature, there are always going to be exceptions to the rule.

There’s always going to be you know, research is not it’s PubMed is not the Bible. And the PubMed, it’s like you have, it looks at one factor. It doesn’t look at all the overtime colors. Okay, like testosterone, they haven’t said testosterone was dangerous, while we look at the population that that that article was revoked, that was retracted, because the population they did the studies on was vets with post-traumatic stress syndrome from the war. No wonder it caused, you know, they come up with testosterone causes cardiovascular disease in older men. Why? Because they know, testosterone heals. So that study was completely false.

Dr. Joel Rosen: Yeah, I find that there’s a paradox with studies because you know, I’m trained as a licensed chiropractic physician, and I’ve done Functional Medicine and niche and genomics and researching the whole medical curriculum, they put high emphasis, then I gotta give praise to two peer-reviewed studies to be able to validate and have scientific data. So there’s a hot, huge emphasis on it, but then you in what you’ve just said, Shawn, with the gaming of the results, or the unbind, the biased sample sizes are the samples are the dependent variables and independent variables have what they want to results to show or if it’s not significant above and beyond the control or placebo, they can really gamify the results to dictate what the pharmaceutical approach will be.

And they end up throwing the baby out with the bathwater, I think but so many things that I would love to address. And I could probably get you on part two because I’m really interested to know about the phenol sulphation tie-in. Because I think that’s a lot of areas where just it’s Uncharted water for a lot of those in the know, let alone those that aren’t in the know. And I’d love to get your insight on that. But back to your original story, and then how you got into what you got into. I guess it’s a blessing, if you look at it, as you had to go through all of those trials and tribulations and background experiences in order to not only heal yourself but to be a healer to other people, as well. And with that being said, now you have an approach where people come to see you, and you look for where those metabolic bottlenecks are.

So I guess maybe if we can succinctly explain when someone comes to you, how, how are you putting weight on how you’re figuring out where those bottlenecks are? Because I know you’re a big proponent of the limbic center wind-up, and how much the autonomic nervous system revs the battery, if you will, no matter what’s going on metabolically with those bottlenecks.

And then, of course, there’s their own subjective feedback and what they feel is working and not working. Then most importantly, the objective numbers that are telling us the story. And then knowing the genomics and the map The Blueprint, which I would agree with, in the sense that it really gives you an idea how those pathways work, and reverse engineering, what needs to be done environmentally nutritionally mindset wise Olympic Lee to be able to come up with a game plan. I guess the question is, Shawn, how do you balance all of those variables? To be able to unlock those metabolic bottlenecks?

Shawn Bean: What I’ve come down to is, is it mean, I mean, teaching this to other clinicians is use the minimal testing necessary, okay? Like, it depends on economics people come into me, and then yourself included with like these mountains, labs, right? The number one thing that you and I both know is the answers there, okay? And the old saying is to listen to the patient, they’ll tell your diagnosis. And that’s so true. But unfortunately, a lot of clinicians, you know, have their eyes set on one thing. So, you know, you come in, like, a person comes in with Hashimotos because they’re coming from stop the thyroid madness.

And the next thing, you know, it’s like, they’re leading you down this rabbit hole, when it’s like, by the way, tell me about your relationship. You know, and then you find out that that person has been, you know, has, for whatever reason been sexually abused by bosses and, you know, had male problems and like, you’re, you know, you’re pointing the rabbit down the rabbit hole here. Okay. Do you think healing your thyroids? No, I said, you need to go and see a counselor. So number one, taking detailed history is crucial. Okay, and just listening. Usually, within the first 15 minutes, it’s like, they give you the mound, you know, it’s like, Listen, I don’t need to see that you have Bartonella this that I just, do you have wine, yes or no? What do you have in your past?

Okay, if we know it’s there, then that’s great. But then it’s like going, it’s like, I’ve been treated for Lyme. I’ve been treated for this. I’ve been treated for that. Then all sudden, you will start asking said, So tell me about your house? Well, we had a leak, and he started going back to the history, then you’re like, then you start to see the symptoms get worse about six months later. And it’s like, Have you been checked for mold? Or fungus or anything like Long goes? Like, No, I said, you went to a Lyme doctor, right?

Yeah. I said, do you understand mycotoxins cross-react with antibodies to line and Epstein Barr and site omega? So if you have cross-reactivity from mycotoxins, guess what, until you address the underlying cause, all those other factors aren’t going to work. Okay, you’re pouring water into the bucket that has holes in it. So basically, what I do when a client comes in, is take a detailed history and try to find out what’s the biggest, as a clinician The best advice I can give another clinician, ask them what treatments worked in the past, and what hasn’t. And that will lead you to potential pathways that are being disrupted. If those pathways are disrupted, then you know, the potential causes of what those pathways are linked back to. Okay. And if you are never clinicians are not sure.

Dr. Ben Lynch does a wonderful job on his pathway planner showing you were showing the pathways of what inhibits it, or you can go through PubMed. And that’s how I learn is I didn’t learn through reading, you know, Dr. Google, I learned from 1000s and 1000s and 1000s of hours looking at studies on rats, because the reason being is there’s no political gain in those. And actually, the rat’s studies, their functionality, not their actuality, link to humans a lot.

Dr. Joel Rosen: And, I’m sorry to interrupt, but I wanted to give a good comment on one of the things you mentioned, as your insight on this. A lot of people will, ask them, hey, what worked, what didn’t work, and then putting a protocol together, and seeing that whatever you did, made them worse. Maybe make a comment on the utility of that, because I think a lot of people end up just stirring up their limbic center and going into overdrive again, with their, with what you did, that stimulated this response that can it’s only results, you know, you don’t want to put a motion on those results. And it would stimulate a response that’s thought of as negative. It’s actually very, very helpful for the clinician, more so than if nothing happened whatsoever.

And maybe even a little bit with there’s just a little bit but I’m not sure um How important that information is number one, and number two, how important it is for that person to not let that negative result or that perceived negative result, along with perceived negative results in blood testing because I see this all the time with my patient base is they get a test back, and I always have hesitant to send it to them before we’ve met, because they have this whole story in their head of Oh, my God, it’s getting worse, I can’t believe it.

And then the things that we’re doing might make them temporarily more inflamed or temporarily kicking up the ocean floor because you’re turning on pathways that have had challenges. If so, I guess the question is, how important is it for both the clinician and the patient alike to understand that this is, is really a hypothesis, of physiology, and there are lots of 40,000 views, but moving parts, and you really have to think of it as nonemotional information versus anything else.

Shawn Bean: I think the best piece of advice there is, is it, this is what I tell a client, I said, Listen, it’s not the fact that you have all these things. It’s the fact that we don’t have all these things I’m concerned about. Okay. And when I tell them, I said, Look at all these imbalances these help explain a lot of your symptoms. This is good news. Okay, when it comes back, and there’s nothing, that’s why I started worrying. And when you do that, what that does is that puts them at ease.

Okay? Because that way, oh, my God looks wrong, me, you got to change the mentality. Instead, look, what’s wrong with you, is explaining what’s going on. So don’t look at it as a bad thing. Look at it as a good thing. And it’s the as I mentioned before, it’s what I don’t see, that concerns me. And there have been probably four cases out of the 1000s that I dealt with, that I went to the doctors and I said, Listen, I cannot give any kind of medical justification for what this person is, is feeling. Okay.

And, I gave them the benefit of the doubt, diversity, three, this, you know, I gave them an option, the optimization. And I said, Listen, this needs to be referred out to, I feel that this case needs to be heard out to a psychiatrist. And guess what, they come back with one child since? Again, there were only three cases out of several 1000s. Well, what happened? Just curious about what happens.

Dr. Joel Rosen: Though, when you want to implement something that you’ve pretty much narrowed down to this pathway or that pathway, and you implement that strategy? And there might be a short glitch. Or there might be a little bit of a response? How do you damage control, I guess, or what do you do from there?

Shawn Bean: Yeah. First of all, one of the things I do is, is when I make recommendations, I always tell them, so listen, by using this submit, we may be stressing this pathway, and these are the things you may experience. And I think having that in-depth knowledge, such as yourself and other practitioners, taking the extra, you know, a minute to explain them will put them at ease, you know, and you don’t want and some people, you know, that are buyer hackers, they want to go down that rabbit hole, you know, if you give this happens, like, listen, I said, Listen, you have a comp gene expression, where certain can sometimes impact comped to some degree. So these are some of the symptoms you might experience because you know, you’re not breaking down your adrenaline properly.

Okay, and as a result, we can offset that if your adrenaline goes up these are some things that you can do, you know, use Boswellia or maybe you’ve seen or worked on that GABA system and work on the braking system okay to try to pull you out of it because I’m one of the things I found I use it to the Rescue Remedy is bought frankincense has been a Rescue Remedy because it kind of like quells the inflammation like right there.

Dr. Joel Rosen: Without any other side effects or…

Shawn Bean: Without any other side effects right? That’s one of the things I found lavender may be another input with bots well yeah, you know people are reacting to this oil that oil then we know that they have a phenol linic acid they have a phenol issue that phenol sulfotransferase issue they have a Celeste late issue. So then you have to work from that, you know, then you have to work from that angle. Then maybe use bots Well yeah. internally with a capsule rather than coming through an essential oil.

Dr. Joel Rosen: Because very slow like no dose is low enough before you start to notice response is that your philosophy is to slow and low or just try to get right in that bell-shaped curve right away. What’s your philosophy on that?

Shawn Bean: You always want to have a buffering system in place before you start to add the gas pedal, I always try to isolate the potential variables, because you’re never going to get all. But you can somewhat, you know, prep them, like maybe there. I said, Listen, one of the one of the things we’re going to help you with is how about we help you better tolerate stress? Okay, so then we work on that we work on them. That’s why I like clinical documentation, When you have an organic acid test, you have a little bit of what’s going on in the playing field.

It’s not like you’re digging, it’s not like you’re digging on, you know, you’re trying to break ground for a new building, and you’re digging any fine stones, where you go in blind it and you buy, you buy a plot, that you had no idea that was built over top of a garage, you know, tires, or you don’t know what you’re getting yourself into.

So clinical testing, is, you know, one of the things I advocate because I like to see who the enemy is, I like to see, how can we litigate any of these potential issues. You know, like, if a person’s endodontic, it’s like, you may want you may not want to give CBD oil. Because if you give CBD oil an anodized person can make more antibiotics, because on the dopamine pathway, even though they have flare up, or how many times you’ve seen people that were schizophrenic they give you they go out to the dopamine pathway when the schizophrenia was actually from the glutamate pathway.

Dr. Joel Rosen: So with medications to write like, oh, SSRIs they’re in the I’ve always said they’re in the wrong. Wrong arena.

Shawn Bean: Arena apps. Yeah. If you do like an organic acid test, you have somewhat of an indication of who you’re dealing with, you’re not going in blind. I mean, I always tell people, I, you know, when people come to me and said, Let’s stop playing guessing games and put the nail in the coffin. Okay, you’ve been dealing with this too long. Okay, there are about four simple tests, they’ll utilize. And once we know what goes going on there, then we know, it’s like one of the biggest tests, I use the Omega Quan.

Dr. Joel Rosen: I was gonna ask you, when you started to talk about I wrote it down here, when you started to talk about the local trains in the before, if you’re doing the Omega quant, so maybe tell the listeners, what the Omega quantity is.

Shawn Bean: Yeah, the Omega quant has been the I always tell my clients, I said this will be the best $100 you’ll ever spend. Because if you don’t stabilize the PG one, PG two, and PG three, and you don’t know there are hidden fires that are going on, okay, people come from client line mold EBV this, that and everything in you know, in the kitchen sink, failing treatment, you do any find out that the racket Donek acid levels are 42. I said, you know, there are three or four fuels to the fire multiplied by a factor of 10. Okay, because you can see or you see a person with, you see a person with a J, one C of like 5.3. But then you do a red blood cell test and see that the arachidonic acid levels are the ratio.

Dr. Joel Rosen: 30 to one off the charts. It’s not even showing.

Shawn Bean: It’s I mean, four to seven, the goal, okay, four to seven is my goal. There are certain labs I don’t like because they don’t follow clinical criteria. Some of the ranges go from like 12 to like 125. I’m like, your break, you know, and I ran side by side, and they’re pretty close. But if the laboratories are giving that information to clinicians, they’re priming, they’re priming false information.

Dr. Joel Rosen: Yeah. Curious, curious, sorry to interrupt you as Have you been pairing that with the inflammation test that looks at thromboxane levels as well? Are you just doing it on its own?

Shawn Bean: I’m kind of just doing it on its own. And we find out that you know, it arachidonic and sometimes the arachidonic acid is is, you know, may not use fish oils, you may want to use things that inhibit that local training pathway.

Dr. Joel Rosen: Okay, going right to SPMs or you are.

Shawn Bean: More so I’ll go to like Boswellia frankincense practice will inhibit that pathway, then that pathway blocks up into the phenol sulfotransferase pathway to so the phenols actually triggered the local trains.

Dr. Joel Rosen: So it’s so interesting because that’s a sort of a newer pathway that I have sort of added to the whole.

Shawn Bean: Yeah, that pathway is the COVID pathway. Right? That’s how I’ve been addressing COVID. There is a wonderful practitioner name Doug Kaufman. He’s been dealing with mycotoxins and Microtonic osis for 35 years. And he said the same thing. Your treat COVID is coming in when you treat them antifungals they’re getting better, the long haulers and that’s how I address them.

I address every person coming in as you know, once I find because as I mentioned before COVID hitch drops the secretary IGA your Bifidobacterium levels go down, that opens up the door to any of the pre-existing infections or exposures that you may have mycotoxins we know through clinical research that at least 43%, up to 50% or more of the buildings have in the United States have been or have water damage.

Okay, so your immune system was able to keep it in check. Now, since this COVID, it unleashed the monster that your body’s been keeping in, and it’s releasing these viruses and activating these lines, I’ve had cases where people had water damage 15 years ago, right? When we look at it, and like you had it all the time, but your body was just keeping in check your immune system was keeping the lock on the cage. Now the monster is out, okay.

Dr. Joel Rosen: you like the organic acid, the Omega check Dutch and there’s a fourth one that you’re doing.

Shawn Bean: Or if there is clinical evidence of the, you know, water damage done, then I’ll go to the My Mic and labs, my Michael Labs is a blood test. It’s the one that’s a peer-reviewed article, it’s based upon clinical evidence. There has been controversy on the urinary tests that you have to take multiple samples throughout the day, to get something experienced to get clinical documentation. Because mycotoxins are, you know, wax and wane, but if it’s in the blood, you can’t, you can’t refute that.

Okay, it’s there. You know, and it’s like the same way you and it’s like, mycotoxins are like 1/10 of a micron, which is the size of viruses. When was the last time that you use a urine test to look to see have EBV? Right. And this, when you start talking like this, it’s like, wow, that makes sense. Now, I’m not disputing the fact that there could be clinical relevance to it. But I have shifted, and the reason being was is, if you have a glutathione deficiency, if you have an oxidative stress issue, you can’t get it out. It’s trapped in the tissue. So if you use the blood, you don’t need to do the proof, you don’t need to put that person at risk of doing a glutathione challenge, okay? I’ve had people that have been sent to the hospital. As a result of that, I mean.

Dr. Joel Rosen: As a challenge. mycotoxin test is you’re, you’re doing.

Shawn Bean: if you know that the person can’t recycle glutathione and you give them glutathione what’s going to happen, you’re gonna have a paradoxical effect. You’re gonna have, you know, you’re gonna have a major herx That person has adrenal insufficiency on top of it, and you could have an adrenal crisis on your hands. So by using the blood, you don’t have to do the prevocational test. You don’t have to do Asana, you don’t have to do anything, just go get blood done. And then not only does that it tells you we’re reacting to so if you come up negative on the IgG, but then you light up like a Christmas treat on the IGE didn’t know you’re dealing with mast cell.

We’re on a urine test. You don’t know if you’re having an immune response or a mast cell response from it. So if you know that you have a Gliotoxin that has a mast cell response, then you know, if you go out to the Gliotoxin, you have to support that. I have a couple of people right now that have Gliotoxin I moved them to singular because what Singulair does is Singulair is used and guess what? acid or aspirin tuck, Oxford aspirin poisoning. So if we know that the phenol sulfotransferase pathway is overloaded, you know there could be high Swiss leadership. So it’s less late is an issue. Then they use the singular offset. And the problem is, that’s why people don’t respond and the history means the problem is not the histamines. It’s local training that they’re responding to.

Dr. Joel Rosen: Yeah, I got all these notes, Shawn and I want to be respectful for our time. I got it, I got actually have another appointment coming up here. But if you’d be willing to do a part two, because I got so much more questions to ask you, I definitely want to go down the rabbit hole of the phenol sulfur pathways. And talking about just the additional layers of the onion bottlenecking. And just go a little bit further down these rabbit holes, they’d love to have you back.

So I’ll save that parting question Till we meet again. But I guess a good parting question might be, let’s say someone’s listening to this, and it is getting somewhat sophisticated. And I do feel like a lot of the people we see have had to become sophisticated because their doctors haven’t done the work for them. And they’re right up in the pilot seat helping to fly the plane. But with that being said, what do you think with everything that you’ve said, so far in maybe less than five minutes, is the best recommendation you can give to someone who’s listening to this that thinks, you know what, it’s insurmountable, I can’t overcome this, I’m never gonna meet with a Shawn or Joel, and I don’t my doctors don’t understand this, what would be the best advice you would give to them to give them a head start on on their recovery process?

Shawn Bean: The first thing I would do in that scenario is assess your environment, assess your environment, work on your water intake, you’re drinking out of plastic bottles, do the simple things. First, the foundational work, okay, get out in the sun. Without the sun, you don’t create sulfate. Without a proper diet, you know, go organic, the best you can. The other thing is, is the thoughts we think the air we breathe, the water we drink, and the food we eat. And also get around a community that is going to support you get around a community that is, you know, a phone call away. To have that support. One of the things that we run into as clinicians and also individuals is a lack of community support and family support. And without that family support and community, it’s going to make the survival.

And also, if you do find the clinician, find a clinician that merges with you. Okay, that you click with, if you’re not getting the right buys for them, don’t waste time. Okay, you’ll know right off the bat. And, you know, I find a clinician that is more known, we need Lyme specialist, meaning traditional medicine, but find one that looks at the bigger picture. Okay, not just oh, genetics or this, that, and everything. It’s amazing too.

Dr. Joel Rosen: Because of the sophisticated and technical and 30 40,000 Few foot intricacies that are going on here. At the end of the day, no matter what, no matter how good your protocol is, or your built protocol specifically for them that’s ever dynamically changing, if you use the word protocol, is the fact that all of the things you just said, will not all the things that you identified will not work if you don’t do the things you just said. Right.

Which is amazing, because that’s where you say, Well, you got to get to the psychologists or psychiatrists to figure out what’s going on here. Because at the end of the day, we’ve identified what’s wrong, we’re not missing a magic pill or magic supplement or a magic test. There are these other things that you’re missing, that you’re not doing that is free. And they’re not always easy, right?

Shawn Bean: No, and everybody’s trying to look for that magic pill, that magic bottle, that magic practitioner, the person who’s in the limelight, okay, has the biggest website has the fanciest Tiktok or whatever. And sometimes it could be fine, that little natural path that was shoved in the corner on a mom polytype shop that just has this basic knowledge that has been profound. You know, maybe just one of my severe lines, severe mold, Canada, wintertime, go to the tanning salon three times a week, what happens is that your Msh is down antidiuretic hormone down steady because our symptoms got better.

That’s because he was lacking sunlight. And that turned on the mitochondria and started the whole process but a jumpstart monitor. So as a clinician, we just want to you know, I have a love-hate relationship with functional medicine. Personally, I think a lot of practitioners do a good job. I think a lot of times are turning mole hills and mountains where we should be turning mountains into molehills. That’s one of the biggest things I see. In fact, Internal Medicine going today is they’re trying to solve.

Dr. Joel Rosen: Well, I mean listening in their defense, they haven’t gone through the trials and tribulations of your own health journey, or had enough miles on the odometer of the sophistication, I guess you would call that wisdom of understanding that, okay. It’s the glue that holds this together. It’s not the parts. Anyways, I gotta keep this for part two. I appreciate your time. We’ll be in contact with each other so that we get that part to go I appreciate your time and I look forward to our next conversation.

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