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Here at Drug Discovery World (DDW) we've been publishing articles written by leading experts in the Drug Discovery, Pharmaceutical, and BioPharmaceutical industries for over 20 years. DDW has grown as a quarterly business review of drug discovery and development, and now we've created this podcast to allow you to listen to our articles on the go. In our journal and this podcast, we cover topics surrounding: drug discovery; drug development; business; chemistry; enabling technologies; informa ...
 
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This episode is for anybody interested in how human beings have altered the world around us since we came on the scene tens of thousands of years ago. University of California Santa Cruz evolutionary biologist Beth Shapiro weaves fascinating and fun personal anecdotes from her own life and research on ancient DNA to tell the story of the evolution …
 
The articles are called “The new synthesis: How synthetic DNA technology is changing drug discovery” and “In vitro drug interaction data critical in drug repurposing”. The first was written by Dr Tim Brears, CEO of Evonetix and Dr Raquel Sanches-Kuiper, Director of Biology at Evonetix. The second was written by Madison Knapp, Marketing Communicatio…
 
In the first article, DDW Editor Lu Rahman takes look at some of the latest imaging innovations available and how it can benefit drug target identification and drug discovery research. In the second, Farah Patell-Socha, PhD, VP Research Products tells Lu Rahman about some of the company’s groundbreaking work in this field and the benefits it is cre…
 
The latest free-to-listen DDW podcast episode covers two articles written for Volume 22, Issue 2 – Spring 2021 of the Drug Discovery World Magazine, narrated by DDW’s Megan Thomas. These articles are titled: “Antibody therapeutics: the other race for immunity against SARS-CoV2” and “Synthesising new solutions for small molecule antibodies”. In the …
 
Among the topics Lu Rahman will be discussing with Wylie will be the key challenges scientists face with biomarker and drug discovery and how high-throughput screening can help alleviate this. High throughput with multiplex is valuable for drug discovery and Wylie will provide insight on this as well offering expert opinion on the future of multipl…
 
This month, we’re reading The Icepick Surgeon: Murder, Fraud, Sabotage, Piracy, and Other Dastardly Deeds Perpetrated in the Name of Science. It’s the new book by Sam Kean, who many might know as the author of the periodic table book The Disappearing Spoon. In what is now his sixth book, Kean tells true stories of what happens when ambition pushes …
 
Bamlanivimab was the first neutralising monoclonal antibody to receive emergency use authorisation from the FDA as a treatment for mild to moderate COVID-19 on 9 November 2020, 94 days after the monoclonal antibody discovery workflow began for the molecule. This achievement, says Eli Lilly, represents the shortest timeline from discovery to public …
 
The latest free-to-listen DDW podcast episode is titled “Recipe for success: collaboration in drug discovery”. It covers three articles: “Why collaboration matters and how to make it a success”; “Platform biotechnologies and the art of collaboration”; and “Cell painting: a vibrant future for phenotypic drug discovery”. In the first article, Matthew…
 
This is the latest episode of the free DDW podcast: “Opportunities to improve drug discovery systems”. It covers two articles written for Volume 22, Issue 1 – Winter 2020/21 of the Drug Discovery World Magazine. The first article is titled “Precision control of protein release to reconfigure bioprocessing and cell-based assays”, where the authors D…
 
In this episode, we’ll tackle Deep Sniff: A History of Poppers and Queer Futures by Adam Zmith. In his first book, Zmith blends historical research with wry observation to tell the story of how amyl nitrites wafted out of the lab and into gay bars, corner shops and bedrooms. Zmith leads readers through the 19th century discovery of nitrites as an a…
 
This is the latest episode of the free DDW podcast, “Putting virology back on the map: the fight against Covid-19”. It covers two articles written for Volume 22, Issue 1 – Winter 2020/21 of the Drug Discovery World Magazine. The first article is a case study titled “New technology in COVID research may accelerate vaccines”, and the second is called…
 
John Couse, Vice President of Scientific Services at Taconic Biosciences discusses the benefits of a robust colony management solution/partner in the drug discovery success; how it can enable companies to scale through resource management and create efficiencies. Couse has extensive knowledge of colony managements solutions and outlines the benefit…
 
In this podcast Dr. Joanna Hawryluk discusses automating the cell culture workflow and explains the importance of cell culture workflow in the drug discovery process and how it can be improved thanks to technological advances. Hawryluk talks us through the cell culture workflow and its relevance within the drug discovery process focussing on the ar…
 
This episode covers two narrated articles written for DDW and is read aloud by Megan Thomas, both of which were published in Volume 22, Issue 1 – Winter 2020/21 of Drug Discovery World. The first article is titled, “Streamlining gene therapy manufacturing will help products reach more patients”, and was written by Akash Bhattacharya, the Senior App…
 
This episode is for all those people who have turned to gardening or amassed houseplants during the Covid lockdowns as we’ll be talking about Lessons from Plants. In it, the biochemist Beronda Montgomery explores the vigorous and creative life of organisms often treated as static and predictable. Writing about plants’ fascinating ability to perceiv…
 
Digital transformations are having wide-ranging and profound impacts within life sciences, creating both opportunities and challenges. One of those challenges is adopting new software systems to drive the transformations. A team from Novartis Institutes of BioMedical Research (NIBR) recognised the need to ensure a good user experience for their in …
 
This is the latest episode of the free DDW podcast, “Paving the way for optimum drug discovery”. It covers two narrated articles written for Volume 22, Issue 1 – Winter 2020/21 Of DDW and they are read aloud by Megan Thomas. These articles are titled: “In vitro models for assessing drug toxicity: new approaches and development” and “Accelerating as…
 
Mathur talks about Twist’s antibody expertise, drawing on the company’s experience and looking at the importance of collaboration. The company has created some successful partnerships and she explains what these look like, why they have been fruitful, and how they have enabled Twist to use its capabilities to maximum effect. Listen now to hear Math…
 
In this month’s episode we’ll talk about Science in Black and White: How Biology and Environment Shape Our Racial Divide by medical anthropologist Alondra Oubré. She delves into the science behind the nature versus nurture debate to expose racially biased research and debunk claims of inborn racial disparities and the gendered brain. The result is …
 
Aydogdu talks us through how the accurate and quantitative analysis of product purity is a fundamental component of effective development of a biotherapeutic protein. But without consistent techniques and high-quality, reproducible results, it is difficult to precisely assess the product’s efficacy and/or safety, potentially delaying, even jeopardi…
 
Get your garlic and crucifix ready as we tackle Kathryn Harkup’s latest book Vampirology: The Science of Horror’s Most Famous Fiend. Harkup is a chemist and science communicator, and an expert at casting a scientific eye on cultural phenomena, literature and film. Her debut, A is for Arsenic – about the poisons in Agatha Christie’s works – featured…
 
Mälarstig is currently responsible for developing and applying strategies for new drug targets and precision medicine. He has extensive experience working in international academic consortia and public–private partnerships such as the SCALLOP consortium. In this podcast he outlines the role of pQTLs in the drug discovery process and the growing imp…
 
The latest episode of the free DDW podcast, “Precision medicine in the era of artificial intelligence”, covers one narrated article of the same title written for DDW and read aloud by Megan Thomas. It was written by Dr Lofti Chouchane and Dr Javaid Sheikh. Dr Chouchane is a professor in the departments of genetic medicine, and microbiology and immu…
 
How do you make a chemical-resistant beaker out of a material as fragile as glass? And how do you tell the temperature of a piece of steel without a thermometer? These are questions Anna Ploszajski tackles in her book Handmade: A Scientist’s Search for Meaning through Making. A materials scientist, engineer, science communicator and occasional stan…
 
The latest DDW Sitting Down With podcast features Raj Indupuri, CEO of eClinical Solutions and he talks to us about clinical trials. Listen to find out why Idupuri believes ‘data is the new fuel that will drive human progress’, the effect of Covid-19 on clinical trials and what the sector can learn from the pandemic to make it better prepared for a…
 
We might like to think that science is purely objective, driven only by scientific principles and free of social disturbances — but this couldn’t be further from the truth. In this episode, we read Chanda Prescod-Weinstein’s debut The Disordered Cosmos, a book exposing how racism and sexism persist across all scientific disciplines. Part introducti…
 
This DDW podcast features Dr Hongshan Li, Applications Manager, Sartorius, discussing advances in cell and protein analysis for virology research. This episode examines virology research - what’s currently happening in the sector and how new advances in technology are helping push forward innovation and drug development. With COVID-19 playing such …
 
This narrated article is called “Why flow cytometry in drug discovery is a real life-saver”, in which Roy, Global Product Manager at Miltenyi Biotec, outlines the benefits of flow cytometry, offering case study examples for its use. Capable of boasting high-throughput, accurate, multiparameter and highly reproducible results, it’s time for drug dis…
 
This is the latest episode of the free DDW podcast, titled Vaccine innovation in the age of Covid-19. It covers two narrated articles written for DDW and read aloud by Megan Thomas. These articles are titled: “Vaccine innovation in the age of Covid-19 & beyond” and “Creating vaccines: Why we should be celebrating the life of the researcher”. The fi…
 
In this episode, we’re looking for answers to the important questions in life like ‘Why do you believe in diets?’ or ‘Why are you working in a bullshit job?’ Biochemist and immunologist Luke O’Neill certainly doesn’t mince words in his new book Never Mind the B#ll*cks, Here’s the Science: A Scientist’s Guide to the Biggest Challenges Facing our Spe…
 
This DDW Sitting Down With episode features Guy Goldberg, Chief Business Officer of RedHill Biopharma. In this episode - With vaccines taking centre stage how critical is the part therapeutics have to play in the pandemic? - Goldberg talks us through Covid-19 therapeutics and their role in the pandemic. Goldberg shares his market insight, the benef…
 
Today's episode is titled The potential of metabolomics & COVID-19 Vaccine Development, and covers 2 articles taken from the most recent Fall issue of DDW. These articles are titled: Why metabolomics has the potential to transform diagnosis and treatment. & COVID-19 Vaccine Development: dethroning evil King Coronovirus These articles were firstly b…
 
This month we find out drug testing has come a long way, as we read The Poison Trials: Wonder Drugs, Experiment and the Battle for Authority in Renaissance Science, the latest book from historian of science and medicine Alisha Rankin. The book tells little-known stories of medicine in 16th century Europe, such as Pope Clement VII’s personal physici…
 
Today's episode is titled: The power of precision and the potential of human tissue chips, and covers 2 articles taken from the most recent issue of DDW. These articles are titled: The power of precision to keep biologics effective and safe & Why we should be interested in human tissue chips These articles were written by Dr Mark Lies, Global Busin…
 
Today's episode on the topic of The Business Side of Drug Discovery, covers 3 articles taken from the most recent Fall issue of DDW. These articles are titled: Building the foundations for post COVID-19 R&D, Opportunity Knocks: Why compound screening libraries are worth the investment, and How to achieve data driven R&D at speed These articles were…
 
This month we’re celebrating 20 years of a popular science classic: Uncle Tungsten: Memories of a Chemical Boyhood by Oliver Sacks. In his memoir, Sacks – who later became a famous neurologist – recounts how he discovered his love for science growing up in the 1930 and 40s. We’ll try to find out whether this book is worth reading (or re-reading), c…
 
Today's episode on the topic of Innovation and Opportunity in Drug Discovery, covers 3 articles taken from the most recent Fall issue of DDW. These articles are titled: Japanese drug development: Where is the innovation, Where are the opportunities in global drug discovery, and New for Old: The value behind drug repurposing. These articles were wri…
 
The Pistoia Alliance has developed a research paper which sets out to consider what the life science, biopharma R&D and healthcare ecosystem might look like in 2030, in particular how the increasing adoption and sophistication of technology will affect companies and patients alike. This article is the second part of a two-part series based on that …
 
Whether you’re looking for a sciencey Christmas present for the young readers in your life or just want to delve into the science of children’s science writing, this kid’s books roundup is for you. We brought together three families and their four children aged three to nine to review Once Upon an Atom by James Carter; I Ate Sunshine for Breakfast …
 
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