Beste Healio podcaster (2025)

1
Gastroenterology Edition: Top Headlines for Week of July 14, 2025 12:50

1d ago12:50

12:50

In this edition, IBD social risks linked to unplanned ED use, anal cancer screening for men with HIV may cut deaths by 65% and more. Read the full coverage here: Nearly two-thirds of adults with IBD experience social risks linked to unplanned ED use Anal cancer screening at age 35 for gay, bisexual men with HIV may cut deaths by 65% ‘Not just a phy…

1
The Tumultuous Tale of Th17-and the IL23/IL17 immune axis 42:40

17d ago42:40

42:40

In this episode, we dive into a two-part story of intrigue starting from a paradigm shift in understanding of T cell biology because of a mouse model of post-measles encephalopathy, to the eventual recognition of the IL-23/17 immune axis. • Intro 0:01 • In this episode 0:12 • Interleukin-17 (IL-17) is a relatively recent discovery 1:34 • The beginn…

1
Orthopedics Edition: Top Headlines for Week of July 14, 2025 8:23

2d ago8:23

8:23

In this edition, we look at knee replacement survivorship, how DEI statements may lead to more women in sports medicine programs and more. Read the full coverage here: Public DEI statements may lead to more women faculty, fellows in sports medicine programs Knee replacements have high long-term survivorship in young patients Aragonite-based scaffol…

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Lung Cancer Edition: Top Headlines for Week of June 23, 2025 13:59

22d ago13:59

13:59

In this edition, DREAM program ‘better than anything’ available, maintenance regimen a potential new standard and more. Read the full coverage here: DREAM program ‘better than anything’ available for patients with advanced lung cancer Maintenance regimen a potential new standard in extensive-stage small cell lung cancer ‘It can save their lives’: A…

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Lung Cancer Edition: Top Headlines for Week of June 2, 2025 13:41

2M ago13:41

13:41

In this edition, reduction efforts prevent 3.8 million lung cancer deaths since 1970, first-line combination should be ‘new standard’ in advanced lung cancer and more. Read the full coverage here: Smoking cessation, reduction efforts prevent 3.8 million lung cancer deaths since 1970 First-line combination should be ‘new standard’ in advanced lung c…

1
History of polymyalgia rheumatica: The origin of the pain & link to giant cell arteritis 46:00

2M ago46:00

46:00

In this episode, we dive into the history of polymyalgia rheumatica, how it was discovered and its link to giant cell arteritis. Intro 0:01 In this episode 0:10 What is polymyalgia rheumatica (PMR)? 0:24 The history of PMR 02:12 PMR in the 1950s: A formally recognized disease 04:52 What was probably PMR in the 1880s 06:27 Naming PMR: Senile rheumat…

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Lung Cancer Edition: Top Headlines for Week of April 28, 2025 13:59

3M ago13:59

13:59

In this edition, reduction efforts prevent 3.8 million lung cancer deaths since 1970, first-line combination should be ‘new standard’ in advanced lung cancer and more. Read the full coverage here: Smoking cessation, reduction efforts prevent 3.8 million lung cancer deaths since 1970 First-line combination should be ‘new standard’ in advanced lung c…

1
Pulmonary hypertension, part 4: The therapeutics, with Dr. Joseph Parambil 1:08:19

3M ago1:08:19

1:08:19

In the final part of this series, Joseph Parambil, MD, walks us through the approach of managing pulmonary hypertension, reviews the pathophysiology and digs into the mechanisms and the differences in the medications. Intro 0:12 In this episode 0:17 Interview with Joseph Parambil, MD 2:53 Reviewing and clarifying pathophysiology prior to initiating…

1
Gastroenterology Edition: Top Headlines for Week of April 14, 2025 12:01

3M ago12:01

12:01

In this edition, sick food service workers top driver of viral foodborne outbreaks in US, no weight loss benefit with semaglutide before bariatric surgery and more. Read the full coverage here: Sick food service workers remain top driver of viral foodborne outbreaks in US ‘We have work to do’: No weight loss benefit with semaglutide before bariatri…

1
Pulmonary hypertension, part 3: Early therapies and vascular physiology 47:44

4M ago47:44

47:44

In this episode, we dive into the early therapies and how our understanding of vascular physiology drastically changed the management of pulmonary hypertension. Intro 0:12 In this episode 0:18 Recap of part 1 & 2 0:31 What part 3 is about 2:31 WHO conference in 1975: Treating pulmonary hypertension 3:48 The Discovery of Non-Steroidal Anti-inflammat…

1
Lung Cancer Edition: Top Headlines for Week of March 17, 2025 12:20

4M ago12:20

12:20

In this edition, recurrence-free survival estimates in less advanced lung cancer, bronchoscopy-guided microwave ablation safe in lung abnormality and more. Read the full coverage here: Recurrence-free survival estimates after surgery higher in less advanced lung cancer Electromagnetic navigation bronchoscopy-guided microwave ablation safe in lung a…

1
Pulmonary hypertension and the rheumatologist, part 2: The history 48:58

5M ago48:58

48:58

In part 2, we dig into the history of pulmonary hypertension. How did this strange diagnosis first get recognized, what does it have to do with cows with thick necks and urinary catheters in the heart? Intro 0:11 In this episode 0:17 Recap of part 1 0:26 How was pulmonary hypertension discovered? 2:38 1891 3:51 1901 5:07 1935 7:02 Hilar dance 12:58…

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Lung Cancer Edition: Top Headlines for Week of February 17, 2025 13:36

5M ago13:36

13:36

In this edition, robotic-assisted bronchoscopy a ‘game changer’, global mortality related to tobacco drops, particulate matter rises and more. Read the full coverage here: Robotic-assisted bronchoscopy a ‘game changer’ in early diagnosis of lung cancer Global lung cancer mortality related to tobacco drops, particulate matter rises in 2019 Osimertin…

1
Pulmonary hypertension and the rheumatologist, part 1: A bit of background 52:39

5M ago52:39

52:39

In this series, we dive into what rheumatologists should know about pulmonary hypertension, starting an interview with Joseph Parambil, MD, where we learn about the disease, when to suspect and how to work up! Intro 0:11 In this episode 0:16 Preview of the four-part series 4:46 Interview with Joseph Parambil, MD 6:27 How did you become interested i…

1
Lung Cancer Edition: Top Headlines for Week of January 20, 2025 11:23

6M ago11:23

11:23

In this edition, combination extends survival vs. standard first-line therapy, integrated care for smoking cessation during lung cancer screening and more. Read the full coverage here: Combination extends survival vs. standard first-line therapy for advanced lung cancer Integrated care ‘best treatment option’ for smoking cessation during lung cance…

1
COVID's role in autoimmunity and where we are in the world of long COVID 33:39

6M ago33:39

33:39

On this episode, hear the 2024 updates on COVID-19, long COVID and the latest developments in research in rheumatology. Hosted by Dr. Leonard Calabrese. Intro 0:12 In this episode 0:21 Coming up on Healio Rheuminations 0:56 COVID-19, long COVID and the rheumatologist with Leonard Calabrese, DO 2:19 Questions 3:12 Long COVID 4:46 Calabrese’s bias 10…

1
Lung Cancer Edition: Top Headlines for Week of December 16, 2024 13:25

7M ago13:25

13:25

In this edition, we bring you Healio’s top lung cancer headlines in 2024. Read the full coverage here: California doctor with lung cancer receives first-of-its-kind lung-liver transplant ‘We were shocked’: Vaping considerably increases lung cancer risk among people who smoke FDA places hold on trial of cell therapy for lung cancer after patient dea…

1
Lung Cancer Edition: Top Headlines for Week of November 11, 2024 10:57

8M ago10:57

10:57

In this edition, single-fraction SBRT outcomes for central lung tumors, adjuvant durvalumab extends survival in limited-stage small cell lung cancer and more. Read the full coverage here: Single-fraction SBRT confers ‘surprisingly excellent’ outcomes for central lung tumors Adjuvant durvalumab extends survival in limited-stage small cell lung cance…

1
The Story of the Flu Vaccine (Re-Release) 47:43

9M ago47:43

47:43

It's that time of year again, everyone rolling up their sleeves to get a flu shot. This throwback episode dives into the history of the struggles pinning down the causative agent of flu and the journey to the vaccine! Intro 0:40 In this episode 1:11 The history of the flu: 1892 1:41 What do we know about viruses? 6:29 Rabies and dead virus 11:17 A …

1
Lung Cancer Edition: Top Headlines for Week of October 14, 2024 10:45

9M ago10:45

10:45

In this edition, FDA approves Rybrevant for advanced lung cancer, screening orders in eligible patients higher with digital health program and more. Read the full coverage here: FDA approves Rybrevant for advanced lung cancer Lung cancer screening orders in eligible patients higher with digital health program FDA approves Opdivo regimen for resecta…

1
Rheumatology/Psoriatic Arthritis Edition: Top Headlines for Week of September 23, 2024 11:48

10M ago11:48

11:48

In this edition, blue-collar workers more likely to miss work or quit due to psoriatic arthritis, infliximab biosimilar increase after release of a third option and more. Read the full coverage here: Blue-collar workers more likely to miss work, quit due to psoriatic arthritis Infliximab biosimilar uptake rapidly increased only after release of a t…

1
Lung Cancer Edition: Top Headlines for Week of September 16, 2024 13:55

10M ago13:55

13:55

In this edition, FDA approves first subcutaneous anti-PD-L1 cancer immunotherapy, ivonescimab ‘may be a new standard’ and more. Read the full coverage here: FDA approves first subcutaneous anti-PD-L1 cancer immunotherapy Ivonescimab extends PFS vs. pembrolizumab in advanced NSCLC, may be ‘a new standard’ Perioperative nivolumab improves outcomes in…

1
DME/Retina Edition: Top Headlines for Week of September 9, 2024 8:40

10M ago8:40

8:40

In this edition, enrollment and dosing complete in phase 1 trial of AIV007, popular benchmarks in clinical practice guidelines and more. Read the full coverage here: Enrollment, dosing complete in phase 1 trial of AIV007 for AMD, diabetic macular edema OCT, visual acuity popular benchmarks in clinical practice guidelines for DME First patient dosed…

1
NSAIDs, Part 3: The rise, fall and rise again of COX-2 inhibition 37:44

11M ago37:44

37:44

In the third episode of the NSAIDs saga, we focus on COX-2 inhibition! Did the hopes and dreams of selective COX-2 inhibition pan out? What can the rise and fall of VIOXX teach us about physiology? Intro 0:11 Recap of part 1 & 2 0:28 In this episode 1:44 Cyclooxygenase 2 (COX-2) and the rat experiment 3:12 What do we know about the prostaglandins? …

1
Rheumatology/Psoriatic Arthritis Edition: Top Headlines for Week of August 19, 2024 11:18

11M ago11:18

11:18

In this edition, drug discounts through Medicare price negotiations, opioid use has fallen 15% annually since 2014 and more. Read the full coverage here: Enbrel, Stelara to be discounted nearly 70% through Medicare price negotiations Opioid use has fallen 15% annually since 2014 in autoimmune rheumatic disease Inhibitor class PsO treatments exhibit…

1
Lung Cancer Edition: Top Headlines for Week of August 12, 2024 15:14

11M ago15:14

15:14

In this edition, low education level raises follow-up risk in screening program, screening judgement strongly influenced by clinicians and more. Read the full coverage here: Low education level raises risk for loss to follow-up in lung cancer screening program Lung cancer screening judgement strongly influenced by clinicians Occupational benzene ex…

1
DME/Retina Edition: Top Headlines for Week of August 5, 2024 11:23

11M ago11:23

11:23

In this edition, sozinibercept combination therapy shows durability, comparable improvements with aflibercept and more. Read the full coverage here: Sozinibercept combination therapy shows durability in patients with DME, neovascular AMD VIDEO: Comparable improvements seen with aflibercept 8 mg vs. 2 mg in DME DPP-IV, SGLT2 and GLP-1 drugs do not i…

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Rheumatology/Psoriatic Arthritis Edition: Top Headlines for Week of July 22, 2024 11:11

12M ago11:11

11:11

In this edition, guselkumab brings ‘stringent’ control through 2 years, SARDs outpatient visits result in opioid prescriptions and more. Read the full coverage here: Guselkumab brings active psoriatic arthritis into ‘stringent’ control through 2 years Nearly one-quarter of all SARDs outpatient visits in US result in opioid prescription FDA approves…

1
Lung Cancer Edition: Top Headlines for Week of July 15, 2024 12:40

12M ago12:40

12:40

In this edition, atezolizumab benefits PD-L1-selected patients with NSCLC, risks persist with e-cigarette use after quitting tobacco smoking and more. Read the full coverage here: Adjuvant atezolizumab benefits PD-L1-selected patients with NSCLC Lung cancer risks persist with e-cigarette use after quitting tobacco smoking COPD, IPF end of life heal…

1
DME/Retina Edition: Top Headlines for Week of July 8, 2024 10:22

1y ago10:22

10:22

In this edition, FDA approves Vabysmo prefilled syringe for retinal diseases, 4D Molecular Therapeutics updates on retinal disease candidates and more. Read the full coverage here: FDA approves Vabysmo prefilled syringe for retinal diseases VIDEO: 4D Molecular Therapeutics shares update on retinal disease candidates FDA approves Eylea biosimilar FY…

1
Rheumatology/Psoriatic Arthritis Edition: Top Headlines for Week of June 24, 2024 10:14

1y ago10:14

10:14

In this edition, extensive psoriasis and IBD history predict difficult-to-treat psoriatic arthritis, targeted therapies demonstrate low risk for serious infection and more. Read the full coverage here: Extensive psoriasis, IBD history predict difficult-to-treat psoriatic arthritis Targeted psoriatic arthritis therapies demonstrate low risk for seri…

1
NSAIDs, Part 2: The Dawn of the Anti-Inflammatories 46:59

1y ago46:59

46:59

In this episode, we dive into the story of aspirin and the development of ibuprofen, ending with the experiments that showed the mechanism of how aspirin actually works. Intro 0:12 Review of part 1 0:28 In this episode 1:04 Blocking prostaglandins and willow leaves 2:26 Edward Stone 3:45 Johann Andreas Buchner 4:16 The chemical structure of salicyl…

1
Lung Cancer Edition: Top Headlines for Week of June 17, 2024 15:04

1y ago15:04

15:04

In this edition, screening program identifies airways disease in previously undiagnosed COPD, positive results show benefits of subcutaneous bispecifics and more. Read the full coverage here: Lung cancer screening program identifies airways disease in previously undiagnosed COPD Positive results in lung cancer show benefits of subcutaneous bispecif…

1
DME/Retina Edition: Top Headlines for Week of June 3, 2024 10:27

1y ago10:27

10:27

In this edition, AI model helps predict anti-VEGF response in DME, Merck to acquire EyeBio and more. Read the full coverage here: VIDEO: AI model helps predict anti-VEGF response in diabetic macular edema Merck to acquire EyeBio VIDEO: IOP remains stable up to 48 weeks with aflibercept 8 mg for DME Phase 2 study of potential DME oral therapy meets …

1
Rheumatology/Psoriatic Arthritis Edition: Top Headlines for Week of May 20, 2024 8:48

1y ago8:48

8:48

In this edition, difficult-to-treat psoriatic arthritis 'not all about the therapies', Samsung biosimilar comparable to etanercept and more. Read the full coverage here: Difficult-to-treat psoriatic arthritis 'not all about the therapies' Samsung biosimilar comparable to etanercept for psoriatic arthritis outcomes at 1 year Boehringer Ingelheim, Qu…

1
The Discovery of Non-Steroidal Anti-inflammatory Drugs (NSAIDs), Part 1 38:05

1y ago38:05

38:05

Humans have had an insatiable appetite for inhibiting production of prostaglandins for centuries! This series delves into the history of aspirin and NSAIDs, looking at the understanding of the prostaglandin pathway. · Intro 0:12 · In this episode 0:23 · What are NSAIDs? 0:53 · Prostaglandins 5:50 · What are prostaglandins? 7:19 · Where do prostagla…

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Lung Cancer Edition: Top Headlines for Week of May 13, 2024 13:04

1y ago13:04

13:04

In this edition, smoking cessation support uptake at lung cancer screenings, glecirasib may deliver ‘efficacy and tolerability advantages’ and more. Read the full coverage here: Uptake of smoking cessation support high when offered at lung cancer screening Glecirasib may deliver ‘efficacy and tolerability advantages’ for KRAS-mutant lung cancer ‘Su…

1
DME/Retina Edition: Top Headlines for Week of May 6, 2024 9:54

1y ago9:54

9:54

In this edition, FDA accepts new drug application for Eluminex, most mentors in vitreoretinal subspecialty are men and more. Read the full coverage here: FDA accepts investigational new drug application for Eluminex DME treatment Most mentors in vitreoretinal subspecialty are men Carotid artery stenosis linked to retinal changes in patients with di…

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Rheumatology/Psoriatic Arthritis Edition: Top Headlines for Week of April 22, 2024 13:32

1y ago13:32

13:32

In this edition, FDA approves Selarsdi as Stelara biosimilar, deucravacitinib improves ‘broad range’ of patient-reported outcomes and more. Read the full coverage here: FDA approves Selarsdi as Stelara biosimilar for psoriasis, psoriatic arthritis Deucravacitinib improves ‘broad range’ of patient-reported psoriatic arthritis outcomes Advanced thera…

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Lung Cancer Edition: Top Headlines for Week of April 15, 2024 12:10

1y ago12:10

12:10

In this edition, durvalumab improves survival in limited-stage small cell lung cancer, most adults do not test homes for radon exposure and more. Read the full coverage here: Durvalumab improves survival in limited-stage small cell lung cancer Survey: Most adults do not test homes for radon exposure, unconcerned about risks FDA fast tracks investig…

1
Urticarial Vasculitis, Part 2: Walking the Balance Beam of Allergy and Rheumatology 35:59

1y ago35:59

35:59

This episode digs into the pathophysiology of urticaria vasculitis from anti-C1q to the story of bradykinin. · Intro 0:11 · In this episode 0:22 · Review of episode 83 1:23 · Listen to previous episode, The Complement System for Dunces 4:09 · Anti-C1q antibodies 6:26 · Lupus, anti-C1q and lupus nephritis 9:33 · What happens when you inject anti-C1q…

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DME/Retina Edition: Top Headlines for Week of April 8, 2024 12:28

1+ y ago12:28

12:28

In this edition, PALADIN study navigates IOP-lowering surgery in DME patients, small-molecule eye drop well-tolerated as treatment for retinal vascular diseases and more. Read the full coverage here: PALADIN study: Navigating IOP-lowering surgery in DME patients for optimal outcomes Small-molecule eye drop safe, well-tolerated as treatment for reti…

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Lung Cancer Edition: Top Headlines for Week of March 11, 2024 12:07

1+ y ago12:07

12:07

In this edition, race identified as risk factor for VTE, FDA approves Rybrevant for treatment of non-small cell lung cancer and more. Read the full coverage here: Race identified as risk factor for VTE after pulmonary resection for lung cancer FDA approves Rybrevant for treatment of non-small cell lung cancer Behavioral health disorders have a ‘big…

1
Urticarial Vasculitis: Attack of the Nettles, Part 1 26:07

1+ y ago26:07

26:07

Is it an allergy or an autoimmune vasculitis, or a little of both? Find out the story of urticarial vasculitis, how this disease was recognized and eventually sorted out from other types of urticaria. · Intro 0:12 · In this episode 0:21 · Case study 1:22 · Chronic spontaneous urticaria, hives and nettles 7:57 · Dermatographism and witchcraft? 10:15…

1
Lung Cancer Edition: Top Headlines for Week of February 12, 2024 13:31

1+ y ago13:31

13:31

In this edition, blood test for lung cancer patients who may benefit from further immunotherapy, invasive procedures following lung cancer screenings and more. Read the full coverage here: Blood test identifies those with lung cancer who may benefit from further immunotherapy Invasive procedures rarely follow false-positive lung cancer screenings S…

1
Lung Cancer Edition: Top Headlines for Week of January 15, 2024 10:49

1+ y ago10:49

10:49

In this edition, FDA places hold on cell therapy trial after patient death, selpercatinib delivers superior outcomes and more. Read the full coverage here: FDA places hold on trial of cell therapy for lung cancer after patient death Selpercatinib delivers superior outcomes, may ‘reduce the burden of NSCLC’ First-line immunotherapy benefits patients…

1
COVID-19, long COVID and the rheumatologist with Leonard Calabrese, DO 29:04

1+ y ago29:04

29:04

What should rheumatologists know about what we've learned about COVID-19 and long COVID in 2023? Hosted by Dr. Leonard Calabrese. · Intro 0:11 · In this episode 0:21 · 2023: current status and controversies 0:35 · What is going on with COVID-19? 01:53 · What do we know about vaccine responses? What should we be telling our patients about vaccines i…

1
Dermatology Edition: Top Headlines for Week of December 18, 2023 8:09

1+ y ago8:09

8:09

In this edition, an advocacy group petitions the FDA for stronger safety warnings for Botox, melanoma regression is associated with improved prognosis and more. Read the full coverage here: Advocacy group petitions FDA for stronger safety warnings for Botox, related drugs Melanoma regression associated with improved prognosis Phase 4 results show V…

1
The Story of the Flu Vaccine 48:05

1+ y ago48:05

48:05

It's that time of year again, everyone rolling up their sleeves to get a flu shot. This episode dives into the history of the struggles pinning down the causative agent of flu and the journey to the vaccine! · Intro 0:12 · In this episode 0:17 · The history of the flu: 1892 3:10 · Rabies and dead virus 10:52 · A Sickness in the Serum, Part 2 14:31 …

1
Dermatology Edition: Top Headlines for Week of December 4, 2023 10:11

1+ y ago10:11

10:11

In this edition, allergic illnesses in children may be inherited from mothers; addressing needs of Muslim patients in dermatology; YouTube content on topical steroid withdrawal exhibits poor reliability and more. Read the full coverage here: Atopic dermatitis, other allergic illnesses in children may be inherited from mothers Addressing needs of Mu…

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