Theoretical Neuroscience podcast

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SISTER WIVES: The Brown Family Plans Garrison's Funeral, Gives NEW Details About His Passing. Justin Baldoni v Blake Lively UPDATES, First Pictures Of Micah Plath’s Broken Nose Have Surfaced!… 36:16

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DANMMMMM…Have I got a show for you! First, a lot of Sister Wives tea - new rumors have surfaced Janelle Brown is leaving the show. Plus, Gabe Brown gives a life update after losing and tragically finding his brother Garrison dead. Sadly, Garrison took his own life in March 2024. Then we head over to discuss the new Welcome To Plathville tea. The first pictures of Micah Plath have surfaced after being beat up by his brother Issac and it doesn’t look good for the future of his modeling career. Lastly, we discuss the latest in the Justin Baldoni v Blake Lively case, Justin is back on social media and it was the perfect social media return. Timestamps: 00:00:00 - Open and new Sister Wives news 00:05:43 - Janelle Brown leaving the show? Sister Wives Closet is officially closed 00:12:45 - A new pic of Micah Plath’s broken nose has surfaced 00:18:18 - Justin Baldoni back on social media and Taylor Swifts team is pissed at Justin Baldoni MY Go Big Podcasting Courses Are Here! Purchase Go Big Podcasting and learn to start, monetize, and grow your own podcast. USE CODE: MOM15 for 15% OFF (code expires May 11th, 2025) **SHOP my Amazon Marketplace - especially if you're looking to get geared-up to start your own Podcast!!!** https://www.amazon.com/shop/thesarahfrasershow Show is sponsored by: Download Cash App & sign up! Use our exclusive referral code TSFS in your profile, send $5 to a friend within 14 days, and you’ll get $10 dropped right into your account. Terms apply Horizonfibroids.com get rid of those nasty fibroids Gopurebeauty.com science backed skincare from head to toe, use code TSFS at checkout for 25% OFF your order Nutrafol.com use code TSFS for FREE shipping and $10 off your subscription Rula.com/tsfs to get started today. That’s R-U-L-A dot com slash tsfs for convenient therapy that’s covered by insurance. SkylightCal.com/tsfs for $30 OFF your 15 inch calendar Quince.com/tsfs for FREE shipping on your order and 365 day returns Warbyparker.com/tsfs make an appointment at one of their 270 store locations and head to the website to try on endless pairs of glasses virtually and buy your perfect pair Follow me on Instagram/Tiktok: @thesarahfrasershow ***Visit our Sub-Reddit: reddit.com/r/thesarahfrasershow for ALL things The Sarah Fraser Show!!!*** Advertise on The Sarah Fraser Show: thesarahfrasershow@gmail.com Got a juicy gossip TIP from your favorite TLC or Bravo show? Email: thesarahfrasershow@gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices…

Theoretical Neuroscience Podcast

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The podcast focuses on topics in theoretical/computational neuroscience and is primarily aimed at students and researchers in the field.

28 episoder

#Science #Biology #Physics #Gaute Einevoll

Theoretical Neuroscience Podcast

11 subscribers

updated for 4 dager siden

Del

Serier hjem•Feed

The podcast focuses on topics in theoretical/computational neuroscience and is primarily aimed at students and researchers in the field.

28 episoder

#Science #Biology #Physics #Gaute Einevoll

Alle episoder

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On whole-cell modeling of bacteria - with Markus Covert - #28 2:04:23

for 4 dager siden2:04:23

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A future computational neuroscience project could be to model not only the signal processing properties of neurons, but also all processes that keep a neuron alive for, say, a 100-year life span. In 2012 the group of the guest published the first such whole-cell model for a very simple bacterium (M. genitalia). In 2020 a model of the larger E. coli bacterium comprising 10.000 equations and 19.000 model parameters was presented. How are such models built, and what can they do?…

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On construction and clinical use of multipurpose neuron models - with Etay Hay - #27 1:13:21

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Numerous neuron models have been made, but most of them are "single-purpose" in that they are made to address a single scientific question. In contrast, multipurpose neuron models are made to be used to address many scientific questions. In 2011, the guest published a multipurpose rodent pyramidal-cell model which has been actively used by the community ever since. We talk about how such models are made, and how his group later built human neuron models to explore network dynamics in brains of depressed patients.…

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On the population code in visual cortex - with Kenneth Harris - #26 1:24:49

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With modern electrical and optical measurement techniques, we can now measure neural activity in hundreds or thousands of neurons simultaneously. This allows for the investigation of population codes, that is, of how groups of neurons together encode information. In 2019 today’s guest published a seminal paper with collaborators at UCL in London where analysis of optophysiological data from 10.000 neurons in mouse visual cortex revealed an intriguing population code balancing the needs for efficient and robust coding. We discuss the paper and (towards the end) also how new AI tools may be a game-changer for neuroscience data analysis.…

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On growing synthetic dendrites – with Hermann Cuntz - #25 1:34:34

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The observed variety of dendritic structures in the brains is striking. Why are they so different, and what determine the branching patterns? Following the dictum “if you understand it, you can build it”, the lab of the guest builds dendritic structures in a computer and explore the underlying principles. Two key principles seem to be to minimize (i) the overall length of dendrites and (ii) the path length from the synapses to the soma.…

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On neuroscience foundation models - with Andreas Tolias - #24 1:31:43

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The term “foundation model” refers to machine learning models that are trained on vast datasets and can be applied to a wide range of situations. The large language model GPT-4 is an example. The group of the guest has recently presented a foundation model for optophysiological responses in mouse visual cortex trained on recordings from 135.000 neurons in mice watching movies. We discuss the design, validation, use of this and future neuroscience foundation models.…

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On human whole-brain models - with Viktor Jirsa - #23 1:55:21

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A holy grail of the multiscale approach for physical brain modelling is to link the different scales from molecules, via cells and local neural networks, up to whole-brain models. The goal of the Virtual Brain Twin project, lead by today’s guest, is to use personalized human whole-brain models to aid clinicians in treating brain ailments. The podcast discusses how such models are presently made using neural field models, starting with neuron population dynamics rather than molecular dynamics.…

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On 40 years with the Hopfield network model - with Wulfram Gerstner - #22 1:27:49

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In 1982 John Hopfield published the paper "Neural networks and physical systems with emergent collective computational abilities" describing a simple network model functioning as an associative and content-addressable memory. The paper started a new subfield in computational neuroscience and led to the influx of numerous theoretical scientists, in particular physicists, to the field. The podcast guest wrote his PhD thesis on the model in the early 1990s, and we talk about the history and present impact of the model.…

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On models for short-term memory - with Pawel Herman - #21 1:47:42

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The leading theory for learning and memorization in the brain is that learning is provided by synaptic learning rules and memories stored in synaptic weights between neurons. But this is for long-term memory. What about short-term, or working, memory where objects are kept in memory for only a few seconds? The traditional theory held that here the mechanism is different, namely persistent firing of select neurons in areas such as prefrontal cortex. But this view is challenged by recent synapse-based models explored by today’s guest and others.…

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On neuro-AI on the boat - part 2 of 2 - with Cristina Savin, Tim Vogels, Mikkel Lepperød, Paul Middlebrooks - #20 1:21:03

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In September Paul Middlebrooks, the producer of the podcast BrainInspired, and I were both on a neuro-AI workshop on a coast liner cruising the Norwegian fjords. We decided to make two joint podcasts with some of the participants where we discuss the role of AI in neuroscience. In this second part we discuss the topic with Cristina Savin and Tim Vogels and round off with a brief discussion with Mikkel Lepperød, the main organizer of the workshop, about what he learned from the workshop.…

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On neuro-AI on the boat - part 1 of 2 - with Ken Harris, Andreas Tolias, Mikkel Lepperød, Paul Middlebrooks - #19 1:19:26

for 33 weeks siden1:19:26

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In September Paul Middlebrooks, the producer of the podcast BrainInspired, and I were both on a neuro-AI workshop on a coast liner cruising the Norwegian fjords. We decided to make two joint podcasts with some of the participants where we discuss the role of AI in neuroscience. In this first part we talk with Mikkel Lepperod, the main organizer about the goal of the workshop, and with Ken Harris and Andreas Tolias about how AI has affected their research neuroscientists and their thoughts about the future of neuro-AI.…

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On electric brain signals - solo episode - #18 1:48:22

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Most of what we have learned about the functioning of the living brain has come from extracellular electrical recordings, like the measurement of spikes, LFP, ECoG and EEG signals. And most analysis of these recordings has been statistical, looking for correlations between the recorded signals and what the animal/human is doing or being exposed to. However, starting with the neuron rather than the data, these electrical brain signals can also be computed from biophysics-based forward models, and this is topic of this podcast.…

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On dendritic function - with Yiota Poirazi - #17 1:27:39

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The most prominent visual characteristic of neurons is their dendrites. Even more than 100 years after their first observation by Cajal, their function is not fully understood. Biophysical modeling based on cable theory is a key research tool for exploring putative functions, and today’s guest is one the leading researchers in this field. We talk about of passive and active dendrites, the kind of filtering of synaptic inputs they support, the key role of synapse placements, and how the inclusion of dendrites may facilitate AI.…

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On consciousness - with Christof Koch - #16 2:04:59

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The greatest mystery of all is why a group of atoms, like the ones constituting me, can feel anything. The mind-brain problem has puzzled philosophers for millennia. Thanks to pioneers like Christof Koch, consciousness studies have recently become a legitimate field of scientific inquiry. In this vintage episode, recorded in February 2021, we discuss many aspects of the phenomenon, including an intriguing candidate theory: Integrated Information Theory.…

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On the simulation tool NEURON - with Michael Hines - #15 1:26:35

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Computational neuroscientists use many software tools, and NEURON has become the leading tool for biophysical modeling of neurons and neural network. Today’s guest has been the leading developer of NEURON since the infancy almost 50 years ago. We talk about how the tool got started and the development up until today’s modern version of the software, including CoreNEURON optimized for parallel execution of large-scale network models on multicore supercomputers.…

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On the molecular memory code - with Sam Gershman - #14 1:20:44

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The idea that memories are stored in molecules was popular in the middle of the 20th century. However, since the discovery of long-term potentiation (LTP) in the 1970s, the dominant view has been that our memories are stored in synapses, that is, in the connections between neurons. Today, there are signs that the interest in molecular memory is returning, and the guest has presented a theory suggesting that molecular and synaptic memory might serve complementary needs for animals.…

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