Beste Luke Timm podcaster (2024)

Chris Garcia, professor at Stanford University and co-founder of several biotech startups, on using protein engineering to advance new treatments for cancer and autoimmune diseases.Av Timmerman Report

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Ep165: Zach Hornby on Tackling Cancer Drug Resistance 1:02:45

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2M ago1:02:45

1:02:45

Zach Hornby, CEO of San Diego-based Boundless Bio, on tackling cancer drug resistance.Av Timmerman Report

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Ep164: Ted Love and Alan Anderson on Raising the Bar for Sickle Cell Disease Patients 56:39

2M ago56:39

56:39

Ted Love, chairman of BIO, and Dr. Alan Anderson, executive director of Sickle Forward, on how to improve quality of life for sickle cell disease patients around the world.Av Timmerman Report

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Ep163: Sarah Boyce on RNA Medicines for Muscle Diseases 1:08:19

3M ago1:08:19

1:08:19

Sarah Boyce, CEO of San Diego-based Avidity Biosciences, on RNA medicines for rare muscle diseases.Av Timmerman Report

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Ep162: Sean McClain on AI for Biologic Drug Discovery 1:05:59

4M ago1:05:59

1:05:59

Sean McClain, CEO of Absci, on using AI to speed up biologic drug discovery.Av Timmerman Report

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Ep161: Jeff Stein on a Long-Lasting Flu Drug 1:08:51

5M ago1:08:51

1:08:51

Jeff Stein, CEO of San Diego-based Cidara Therapeutics, on a long-lasting drug against flu.Av Timmerman Report

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Ep160: Abe Ceesay on Precision Neuroscience 1:08:48

5M ago1:08:48

1:08:48

Abe Ceesay, CEO of Boston-based Rapport Therapeutics, on a precision medicine approach to neuroscience drug discovery.Av Timmerman Report

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Ep159: Jimi Olaghere on Being Functionally Cured of Sickle Cell Disease 1:07:22

5M ago1:07:22

1:07:22

Jimi Olaghere is one of the first patients to have been functionally cured of sickle cell disease with a CRISPR gene-edited cell therapy.Av Timmerman Report

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Ep158: David Younger and Randolph Lopez on SynBio & AI for Discovery 1:00:44

6M ago1:00:44

1:00:44

David Younger and Randolph Lopez, co-founders of A-Alpha Bio, on using synthetic biology and AI to discover new biologic drugs.Av Timmerman Report

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Ep157: Vineeta Agarwala of A16Z on Investing in AI for Drug Discovery 56:33

7M ago56:33

56:33

Vineeta Agarwala, general partner at A16Z's Bio & Health fund, on investing in AI for drug discovery.Av Timmerman Report

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Ep156: David Liu on New Tools and Techniques for Biology 1:52:57

7M ago1:52:57

1:52:57

David Liu, professor of chemistry at Harvard University and co-founder of multiple biotech companies, including Beam Therapeutics and Prime Medicine.Av Timmerman Report

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Ep155: Valerie Daggett on Early Detection, and Treatment, of Alzheimer's 1:02:37

8M ago1:02:37

1:02:37

Valerie Daggett, founder and CEO of Seattle-based AltPep, on early detection and treatment of Alzheimer's.Av Timmerman Report

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Ep154: Robert Ang on CRISPR to Protect Bone Marrow & Attack Cancer 1:03:14

9M ago1:03:14

1:03:14

Robert Ang, CEO of Cambridge, Mass.-based Vor Bio, on using CRISPR gene editing to alter bone marrow transplants and improve treatment of acute myeloid leukemia.Av Timmerman Report

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Ep153: Rick Young on Studying Gene Expression for Drug Discovery 1:01:43

10M ago1:01:43

1:01:43

Rick Young, professor at MIT and co-founder of Syros Pharmaceuticals, CAMP4 Therapeutics, Omega Therapeutics, and Dewpoint Therapeutics, on studying gene expression for drug discovery.Av Timmerman Report

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Ep152: Jens Eckstein on Investing in Healthy Aging 1:05:05

10M ago1:05:05

1:05:05

Jens Eckstein, investment partner at Hevolution Foundation, on investing in healthy aging.Av Timmerman Report

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Ep151: Shelley Force Aldred and Nathan Trinklein on Bispecific Antibodies for Cancer 1:03:55

11M ago1:03:55

1:03:55

Shelley Force Aldred and Nathan Trinklein, co-founders of Rondo Therapeutics, on the opportunity with bispecific antibodies for cancer.Av Timmerman Report

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Ep150: Jeff Jonker on the Small Molecule Drug Discovery Renaissance 1:03:48

11M ago1:03:48

1:03:48

Jeff Jonker, CEO of San Diego-based Belharra Therapeutics, on the renaissance in small molecule drug discovery.Av Timmerman Report

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Ep149: Nancy Stagliano on Precision Neuroscience 1:01:53

12M ago1:01:53

1:01:53

Nancy Stagliano, CEO of South San Francisco-based Neuron23, on bringing precision medicine to neuroscience drug discovery.Av Timmerman Report

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Ep148: Diana Brainard on the Fight Against Infectious Disease 1:03:27

1y ago1:03:27

1:03:27

Diana Brainard, CEO of AlloVir, on leading the fight against infectious diseases.Av Timmerman Report

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Ep147: Reid Huber on Investing in the Future of Medicine 1:08:41

1y ago1:08:41

1:08:41

Reid Huber, partner at Third Rock Ventures, on investing in the future of medicine.Av Timmerman Report

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Ep146: Jeff Huber on Life in Tech and Biotech 1:47:05

1y ago1:47:05

1:47:05

Jeff Huber, co-founder and general partner at Triatomic Capital, on his career path in tech, and then biotech.Av Timmerman Report

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Ep145: Lori Lyons-Williams on Targeted Radiopharmaceuticals for Cancer 1:06:39

1y ago1:06:39

1:06:39

Lori Lyons-Williams, CEO of Abdera Therapeutics, on developing targeted radiopharmaceuticals for cancer.Av Timmerman Report

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Ep144: Turning the Tables, Rob Perez Interviews Me 1:04:58

1y ago1:04:58

1:04:58

Turning the Tables, Rob Perez Interviews MeAv Timmerman Report

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Ep143: Zach Weinberg and Alexis Borisy on Freeing the Biotech Founders 1:10:25

1y ago1:10:25

1:10:25

Zach Weinberg and Alexis Borisy of Curie.Bio on Freeing the Biotech FoundersAv Timmerman Report

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Ep142: Fred Appelbaum on how 'Living Medicine' Came to Be 55:54

1y ago55:54

55:54

Fred Appelbaum, a physician, scientist and leader at the Fred Hutchinson Cancer Center, on 'Living Medicine,' his new book about the development of bone marrow transplantation and the rise of cell therapy.Av Timmerman Report

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Ep141: Colin Hill on Digging Deep into Data, Finding New Drug Targets 1:09:30

1+ y ago1:09:30

1:09:30

Colin Hill, co-founder and CEO of Aitia, on digging deep into biological datasets and finding new drug targets.Av Timmerman Report

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Ep140: Yung Lie on Supporting Young Scientists with Bold, Brave Ideas 1:02:40

1+ y ago1:02:40

1:02:40

Yung Lie, president and CEO of Damon Runyon Cancer Research Foundation, on advancing cancer research by supporting young scientists with bold and brave ideas.Av Timmerman Report

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Ep139: Kevin Conroy on Early Detection of Cancer 1:08:28

1+ y ago1:08:28

1:08:28

Kevin Conroy, CEO of Exact Sciences, on early detection of cancer.Av Timmerman Report

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Ep138: Jodie Morrison on Becoming a Biotech CEO 1:00:17

1+ y ago1:00:17

1:00:17

Jodie Morrison, acting CEO of Q32Bio, on becoming a biotech CEO.Av Timmerman Report

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Ep137: Aaron Ring on Immunotherapy for Cancer & More 56:37

1+ y ago56:37

56:37

Aaron Ring, a scientist at Yale moving to the Fred Hutchinson Cancer Center, on applying immunology and protein engineering for cancer therapy and more.Av Timmerman Report

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Ep136: Deborah Palestrant on Building Biotech Startups 52:52

1+ y ago52:52

52:52

Deborah Palestrant, partner at 5AM Ventures and head of the 4:59 initiative, on building biotech startups.Av Timmerman Report

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Ep135: John Maraganore on Developing a New Class of Medicines 1:03:51

1+ y ago1:03:51

1:03:51

John Maraganore, former founding CEO of Alnylam Pharmaceuticals, on his life in biotech and developing RNA interference as a new class of medicine.Av Timmerman Report

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Ep134: Emile Nuwaysir on In Vivo Gene Editing Therapies 1:16:22

1+ y ago1:16:22

1:16:22

Emile Nuwaysir, CEO of Boston-based Ensoma, on developing off-the-shelf in vivo gene editing therapies.Av Timmerman Report

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Ep133: Catherine Stehman-Breen on Epigenetic Editing Therapies 1:10:33

1+ y ago1:10:33

1:10:33

Catherine Stehman-Breen, CEO of Boston-based Chroma Medicine, on developing epigenetic editing therapies.Av Timmerman Report

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Ep132: Eric Dobmeier on Treating Kidney Disease 1:05:44

1+ y ago1:05:44

1:05:44

Eric Dobmeier, CEO of Seattle-based Chinook Therapeutics, on new strategies for treating kidney diseases.Av Timmerman Report

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Ep131: Ryan Watts on Neuroscience Drug R&D 1:05:32

1+ y ago1:05:32

1:05:32

Ryan Watts, CEO of South San Francisco-based Denali Therapeutics, on neuroscience drug discovery and development.Av Timmerman Report

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Ep130: David Hallal on a Life in Biotech & the Cell Therapy Wave 1:09:29

1+ y ago1:09:29

1:09:29

David Hallal, CEO of ElevateBio, on a long career in biotech and the coming 50-year opportunity in cell therapy and gene therapy.Av Timmerman Report

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Ep129: Joanne Smith-Farrell on Engineered B-Cell Therapies 1:11:43

1+ y ago1:11:43

1:11:43

Joanne Smith-Farrell, CEO of Cambridge, Mass.-based Be Biopharma, on Engineered B-Cell Therapies for Cancer & Rare Diseases.Av Timmerman Report

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Ep128: Rick Berke on Building a Biotech Journalism Outlet to Last 1:00:34

2y ago1:00:34

1:00:34

Rick Berke, co-founder and executive editor of STAT, on building a biotech journalism outlet to last.Av Timmerman Report

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Ep127: Jeb Keiper on Computational Drug Discovery 1:09:41

2y ago1:09:41

1:09:41

Jeb Keiper, CEO of Nimbus Therapeutics, on computational drug discovery, an unusual business model, and an important new Tyk2 inhibitor for psoriasis and other forms of autoimmunity.Av Timmerman Report

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Ep126: DA Wallach on Becoming a Biotech VC 1:11:38

2y ago1:11:38

1:11:38

DA Wallach, founder and general partner of TIME Bioventures, on becoming a biotech venture investor.Av Timmerman Report

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Ep125: Barry Greene on a New Drug for Depression 1:04:52

2y ago1:04:52

1:04:52

Barry Greene, CEO of Cambridge, Mass.-based Sage Therapeutics, on plans to introduce a new type of treatment for depression and postpartum depression.Av Timmerman Report

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Ep124: Shehnaaz Suliman on Delivery of Genetic Medicines 1:09:53

2y ago1:09:53

1:09:53

Shehnaaz Suliman, CEO of ReCode Therapeutics, on lipid nanoparticle delivery of genetic medicines.Av Timmerman Report

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Ep123: Tariq Kassum on Single-Cell Analysis for Drug Discovery 1:15:26

2y ago1:15:26

1:15:26

Tariq Kassum, CEO of Cambridge, Mass.-based Celsius Therapeutics, on using single cell technology for drug discovery.Av Timmerman Report

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Ep122: Aetna Wun Trombley on Extracellular Protein Degraders 1:00:04

2y ago1:00:04

1:00:04

Aetna Wun Trombley, CEO of Lycia Therapeutics, on extracellular protein degraders.Av Timmerman Report

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Ep121: Samantha Truex on Going Upstream Against Severe Asthma 1:03:49

2y ago1:03:49

1:03:49

Samantha Truex, CEO of Upstream Bio, on a new approach to treating severe asthma and other inflammatory diseases.Av Timmerman Report

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Ep120: Tim Lu on Gene Circuits for Cell Therapy 1:04:14

2y ago1:04:14

1:04:14

Tim Lu, CEO of Senti Biosciences, on developing gene circuits for cell therapy.Av Timmerman Report

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Ep119: Jo Viney on Discovering Treatments for Autoimmune Disease 1:02:42

2y ago1:02:42

1:02:42

Jo Viney, CEO of Seismic Therapeutic, on discovering new treatments for autoimmune disease.Av Timmerman Report

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Ep118: Ivan Liachko on Assembling Accurate Genomes and Interactomes 1:08:08

2+ y ago1:08:08

1:08:08

Ivan Liachko, CEO of Seattle-based Phase Genomics, on assembling accurate genomes and interactomes. He also discusses immigrating from Ukraine as a child, and what brought him and his family to the US.Av Timmerman Report

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