Episode 4: Targeting The Dopamine System To Treat Alcohol Dependence CNS podcast

Innhold levert av The Department of Clinical Neuroscience, Karolinska Institutet, The Department of Clinical Neuroscience, and Karolinska Institutet. Alt podcastinnhold, inkludert episoder, grafikk og podcastbeskrivelser, lastes opp og leveres direkte av The Department of Clinical Neuroscience, Karolinska Institutet, The Department of Clinical Neuroscience, and Karolinska Institutet eller deres podcastplattformpartner. Hvis du tror at noen bruker det opphavsrettsbeskyttede verket ditt uten din tillatelse, kan du følge prosessen skissert her https://no.player.fm/legal.

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Episode 4: Targeting the Dopamine System to Treat Alcohol Dependence

9y ago 24:44

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In this episode we meet Pia Steensland and Nitya Jayaram-Lindström from the Centre of Psychiatric Research, Department of Clinical Neuroscience to discuss their research on the evaluation of a dopamine stabiliser OSU6162 for alcohol dependence. Their translational studies show that in alcohol dependent patients OSU6162 reduces craving for alcohol and the animal studies demonstrate that OSU6162 normalises the level of dopamine in the brain reward system, following long- term alcohol consumption which could be the mechanism by which this compound mediates in effects. We discuss the implications of these findings for the indication of alcohol dependence and future directions with regards to OSU6162. To read more about on the studie visit http://ki.se/en/news/one-step-closer-to-a-new-drug-for-alcohol-dependence and to read more about their research in general visit http://ki.se/en/cns/johan-francks-research-group

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#Medicine #Science #Clinical #Neuroscience #Karolinska #Institutet #Karolinska Institutet #Department Of Clinical Neuroscience At Karolinska Institutet #Department Of Clinical Neuroscience