#351 - RNA as Catalyst: A Dialogue with Thomas Cech

Converging Dialogues

In this episode, Xavier Bonilla has a dialogue with Thomas Cech about RNA as a major catalyst in organic systems. They discuss why RNA does not get discussed as much as DNA, basics of DNA, RNA as a catalyst, and the splicing capabilities of RNA. They also talk about transcription, translation, and splicing, RNA as internal catalyst and external catalyst, and the origins of life. They talk about telomeres and extended life, different types of RNA, mRNA vaccines, CRISPR, and many more topics.

Thomas Cech is distinguished professor of chemistry and biochemistry at the University of Colorado-Boulder. He has been an Investigator at the Howard Hughes Medical Institute (HHMI) since 1988 and was President of HHMI in 2000-2009. He has his PhD from the University of California-Berkeley and completed his postdoctorate at MIT. His main interests are in RNA and telomeres. He received the Nobel Prize in Chemistry (with Sidney Altman) in 1989 and the National Medal of Science in 1995. He is the author of the latest book, The Catalyst: RNA and the Quest to Unlock Life’s Deepest Secrets.

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