#68 Phylogenetic inference from raw reads and Read2Tree with David Dylus

the bioinformatics chat

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2+ y ago 49:11

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In this episode, David Dylus talks about Read2Tree, a tool that builds alignment matrices and phylogenetic trees from raw sequencing reads. By leveraging the database of orthologous genes called OMA, Read2Tree bypasses traditional, time-consuming steps such as genome assembly, annotation and all-versus-all sequence comparisons.

Links:

Inference of phylogenetic trees directly from raw sequencing reads using Read2Tree (David Dylus, Adrian Altenhoff, Sina Majidian, Fritz J. Sedlazeck, Christophe Dessimoz)
Background story
Read2Tree on GitHub
OMA browser
The Guardian’s podcast about Victoria Amelina and Volodymyr Vakulenko

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#Bioinformatics #Genetics #Algorithms #Ngs #Roman Cheplyaka #Biology #Science #Natural Sciences #Sequence #Genomics