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Ep. 58: “Redesigning Proteins” Featuring Dr. Jamie Spangler

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Manage episode 371624848 series 2895470
Innhold levert av The Immunology Podcast. Alt podcastinnhold, inkludert episoder, grafikk og podcastbeskrivelser, lastes opp og leveres direkte av The Immunology Podcast eller deres podcastplattformpartner. Hvis du tror at noen bruker det opphavsrettsbeskyttede verket ditt uten din tillatelse, kan du følge prosessen skissert her https://no.player.fm/legal.

Jamie Spangler

Guest:

Dr. Jamie Spangler is an Assistant Professor at Johns Hopkins. Her lab implements a unique structure-based engineering approach to elucidate the determinants of protein activity and inform drug development. She talks about designing cytokine mimetics and how engineered cytokines could be used as therapeutics.

Featured Products and Resources:

The Immunology Science Round Up

Microenvironment Reprogramming in Cancer Progression – Researchers developed a high-resolution tumor microenvironment atlas for gastric adenocarcinoma.

Tregs and Cell Therapy for Parkinson’s Disease – Co-transplanting Tregs with iPSC-derived neurons improves cell survival.

How Hepatitis C Hides from the Immune System – Flavin adenine dinucleotide capping of the hepatitis C virus protects RNA from RIG-I mediated innate immune recognition.

Mast Cells in Antigen-Avoidance – Mast cell activation in the stomach lining releases leukotrienes to affect food avoidance behavior.

Allergic Responses and Behavior Modification – Researchers showed that allergic sensitization drives antigen-specific avoidance behavior in mouse models of food allergy.

Image courtesy of Dr. Jamie Spangler

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109 episoder

Artwork
iconDel
 
Manage episode 371624848 series 2895470
Innhold levert av The Immunology Podcast. Alt podcastinnhold, inkludert episoder, grafikk og podcastbeskrivelser, lastes opp og leveres direkte av The Immunology Podcast eller deres podcastplattformpartner. Hvis du tror at noen bruker det opphavsrettsbeskyttede verket ditt uten din tillatelse, kan du følge prosessen skissert her https://no.player.fm/legal.

Jamie Spangler

Guest:

Dr. Jamie Spangler is an Assistant Professor at Johns Hopkins. Her lab implements a unique structure-based engineering approach to elucidate the determinants of protein activity and inform drug development. She talks about designing cytokine mimetics and how engineered cytokines could be used as therapeutics.

Featured Products and Resources:

The Immunology Science Round Up

Microenvironment Reprogramming in Cancer Progression – Researchers developed a high-resolution tumor microenvironment atlas for gastric adenocarcinoma.

Tregs and Cell Therapy for Parkinson’s Disease – Co-transplanting Tregs with iPSC-derived neurons improves cell survival.

How Hepatitis C Hides from the Immune System – Flavin adenine dinucleotide capping of the hepatitis C virus protects RNA from RIG-I mediated innate immune recognition.

Mast Cells in Antigen-Avoidance – Mast cell activation in the stomach lining releases leukotrienes to affect food avoidance behavior.

Allergic Responses and Behavior Modification – Researchers showed that allergic sensitization drives antigen-specific avoidance behavior in mouse models of food allergy.

Image courtesy of Dr. Jamie Spangler

Subscribe to our newsletter!

Never miss updates about new episodes.

Subscribe
  continue reading

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