Welcome to Zach Horowitz, where amazing things happen.
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a16z Live is the place to listen to recorded live discussions and events featuring, hosted, or co-hosted by a16z partners (with outside voices too). As a reminder, all content posted here is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Views expressed are those of the individuals and not the views of Andreessen Horowitz, please see a16z.com/disclosures for more. To learn more about the broader a16z Podcast network and ...
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In the Vault: AI and Banking Innovation with Tim Karpoff of Citi
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a16z general partner David Haber and fintech partner Marc Andrusko talk to Tim Karpoff, the Global Head of Strategy at Citi, where he guides the bank’s core focus areas, as well as future investment in emerging tech like AI. The conversation covers the shifting landscape of banking policy and regulation, the increasingly important role startups are…
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Building the World’s Most Trusted Driver with Waymo's Dmitri Dolgov
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Waymo co-CEO Dmitri Dolgov joined a16z general partner David George to discuss how Waymo is using genAI to help them build safer, sustainable, and more accessible transportation. In the conversation, Dmitri talks about the potential of embodied AI, the value of simulations and building training data, and his approach to leading a company focused on…
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Bringing Production-Ready GenAI to the Enterprise
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As genAI expands through the enterprise, many leaders are figuring out how to evolve their genAI prototypes into production-ready tools. Pinecone CEO Edo Liberty and LangChain CEO Harrison Chase discuss which parts of the stack to build or buy, how to improve out-of-the-box models by helping customers select and ingest the right data, and picking t…
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In the Vault: Public Market and Macro Perspectives with Mark Casey of Capital Group
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In this episode, which took place at a16z's Connect Fintech event, a16z General Partner David George interviews Capital Group's Mark Casey on his investment philosophy, what sends him into what he calls "barnacle mode," his preference for customer-focused North Star metrics, and more. 0:00-1:42 Intro 1:42-5:58 Approach to investing 5:58-8:20 What C…
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In the Vault: New Applications in Fintech with Plaid’s Zach Perret and Marqeta’s Simon Khalaf
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In this conversation, which took place at a16z's Connect Fintech event, a16z General Partner Angela Strange, Plaid CEO and cofounder Zach Perret, and Marqeta CEO Simon Khalaf discuss how AI will shape the future of banking, the battle between payment rails in the U. S., and how there's still opportunity to transform the basic credit card into a ful…
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In the Vault: Turning Developers Into Clients With Marco Argenti From Goldman Sachs
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In a new episode of In the Vault, a16z General Partner David Haber talks with Marco Argenti, the chief information officer at Goldman Sachs, about bringing fintech processes into financial services, turning developers into clients, and how AI is a major inflection point in the history of technology. 0-1:30 Intro 1:30-12:05 From tech to financial se…
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In the Vault: Finding a Single Source of AI Truth With Marty Chavez From Sixth Street
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In a new episode of In the Vault, a16z General Partner David Haber talks with Marty Chavez, a partner and vice chairman of Sixth Street Partners, about the foundational role he’s had in merging technology and finance throughout his career, and the magical promises and regulatory pitfalls of AI. 0-1:30 Intro 1:30-12:50 Marty's history and transition…
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In the Vault: Placing Multiple Bets on a ‘Mosaic of Solutions’ With Former Global Payments CEO Jeff Sloan
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In a new episode of In the Vault, a16z General Partner Angela Strange talks with Jeff Sloan, former CEO of Global Payments, about how he was early to spot significant industry trends, how to make bets that move an organization, and the sea change that AI represents for the financial services industry. 0-1:40 Intro 1:40-8:15 Joining Global Payments …
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Harnessing Ecosystem-Led Growth with Crossbeam's Bob Moore
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In this SaaS era, partnering with no one means competing with everyone. How the best companies take advantage of ecosystem-led growth—or where they sit in the SaaS ecosystem to improve acquisition, expansion, and access to new markets, as discussed by a16z general partner Sarah Wang and Crossbeam CEO Bob Moore. [00:01:43] The birth of ecosystem-led…
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AI Revolution: Bringing AI to the Masses with Quora's Adam D'Angelo
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CEO of Quora Adam D’Angelo discusses how building infrastructure for creators can democratize AI, in conversation with a16z’s David George. [01:07] Social networks as compliment to AI [03:59] Poe: bringing AI to the masses [05:51] The future of AI is multi-model and multimodal [08:11] Is the model the product? [11:31] Building AI infrastructure for…
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Recruiting and Retaining the Right Executive Talent
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Hiring the right executives at the right time is the key to scaling your company. But to many founders, the executive search and hiring process can feel like a black box. a16z talent partner Matt Oberhardt dives deep into the executive search process with Kelli Dragovich and Nolan Church on the HR Heretics podcast. [00:01:21] How a16z talent partne…
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Building Better Communities with Flock Safety
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Respecting privacy and building trust with communities is essential to effectively integrate technology into public safety. a16z general partner David Ulevitch, Flock Safety’s Garrett Langley, and Las Vegas Metropolitan Police Department Sheriff Kevin McMahill discuss how to build and implement products that communities can trust. [00:01:22] Flock …
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My First 16: Launching a New Category with Modern Treasury's Dimitri Dadiomov
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In this episode, a16z partner Seema Amble talks with Dimitri Dadiomov, the co-founder and CEO of payment operations platform Modern Treasury, about the challenges of creating a new category, hiring for marketing before you hire for sales, and why developing new features is similar to birding. 0:00 - 1:20 Intro 1:20 - 8:55 The founding of Modern Tre…
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My First 16: Creating a Supportive Builder Community with Plaid's Zach Perret
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In this episode, a16z partner Seema Amble talks with Zach Perret, the co-founder and CEO of Plaid, about how Plaid built a community in the early days to acquire customers, how they tracked “free radicals,” and how to orient your first customers around speed. 0 - 1:09 Intro 1:09 - 9:57 Plaid history 9:57 - 16:39 First customers 16:39 - 26:45 Pricin…
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My First 16: Welding Yourself to Early Customers with Marqeta's Jason Gardner
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In this episode, a16z partner Seema Amble talks with the founder and current executive chairman of Marqeta Jason Gardner about what it means to be welded to your customer and how to expand in multiple verticals. 0:00-1:10 Intro 1:10-6:01 Marqeta's beginning 6:01-9:15 First customers 9:15-16:25 "Magic" product market fit 16:25-24:58 Building custome…
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My First 16: Doubling Down on Founder-Led Sales with Pilot's Waseem Daher
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In a new episode of My First 16, a16z partner Seema Amble talks with co-founder and CEO of Pilot Waseem Daher on how he thought about the importance of charging, how secondary signals often matter in an area like accounting, and never stepping away from doing founder-led sales. 0:00 - 1:45 Intro 1:45 - 6:36 Pilot's beginning 6:36 - 13:25 First cust…
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Sales–Product Tension, the Secret to Segment’s Success
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Sales wants more features. Product gets bogged down with one-off requests. Progress and growth grinds to a halt. It's a familiar story. How Segment turned the sales-product tension into a successful $3.2B acquisition, as told by the former CRO Joe Morrissey and former chief product development officer Tido Carriero. [00:01:29] Joe's start as CRO [0…
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My First 16: Competing in a Crowd of Incumbents with Mercury's Immad Akhund
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In a new episode of My First 16, a16z partner Seema Amble talks with co-founder and CEO of Mercury Immad Akhund about the idea of a “minimum delightful product” in fintech, doing the spreadsheet math on unit economics early on, and how to compete in a category already filled with incumbents. 0:00 - 1:28 Introduction 1:28 - 9:14 History of Mercury 9…
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AI Revolution: Where We Go From Here with OpenAI's Mira Murati
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As CTO of OpenAI, Mira Murati oversaw the development and release of GPT-4 and ChatGPT. Here she tells Martin Casado the story behind the release of ChatGPT—and what it tells us about the future of AI and human-machine interactions. [0:59] Mira's background [4:55] Math, physics, and AI [7:31] Natural language interfaces [10:51] OpenAI Roadmap [17:4…
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AI Revolution: Leveling Up with Roblox's David Baszucki
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Roblox cofounder and CEO David Baszucki and a16z's Jonathan Lai discuss the ways AI is changing games and virtual worlds, as well as how we create them. [1:00] Generative AI in games [4:56] Fully personalized playthroughs [7:50] Roblox's generative model [11:28] Future of interfaces [13:25] impact on creators [16:36] NPCs as copilots [18:49] VR & s…
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AI Revolution: Digital Biology with insitro's Daphne Koller
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Daphne Koller is the founder and CEO of insitro, a company using AI and machine learning to engineer drug discovery. In this conversation with a16z's Vijay Pande, she discusses how an LLM for cells could revolutionize drug discovery and how to bridge the technological and cultural divide between building with atoms and building with bits. [0:59] Wh…
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AI Revolution: Food Fights in the Enterprise with Databricks' Ali Ghodsi
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Ali Ghodsi, CEO and cofounder of Databricks, and Ben Horowitz, cofounder of a16z, explain the data wars happening inside and outside enterprises and how they could impact the evolution of LLMs. [0:59] Why is it so hard for enterprises to adopt AI? [3:29] Data wars [4:49] Big vs. small LLMs [8:35] Finetuning [14:14] Open source AI [18:13] Benchmarks…
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AI Revolution: Universally Accessible Intelligence with Character.ai's Noam Shazeer
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Noam Shazeer, Character.ai CEO and cofounder, talks to a16z's Sarah Wang about the dawn of universally accessible intelligence, the compute it will take to power it, and his pursuit of AGI's first use... [0:59] Real Noam vs. AI Noam [6:14] Next unlocks [8:11] First use case for AGI [11:06] Building a full-stack LLM [13:33] Noam calculates global co…
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AI Revolution: Improving AI with Anthropic's Dario Amodei
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Cofounder and CEO of Anthropic Dario Amodei unpacks how far can scaling laws take us and how can AI be used to improve AI, in conversation with a16z's Anjney Midha. [0:59] Dario's background [2:45] GPT-2's emergent capabilities [5:16] Scaling laws [8:55] Why are there so many physicists in AI? [11:58] Constitutional AI [18:29] Anthropic's Roadmap T…
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AI Revolution: Democratizing Design with Figma's Dylan Field
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Will AI take all the design jobs? Dylan Field, founder and CEO of Figma, looks at the relationship between designers, developers, and AI, in conversation with a16z's David George. [0:58] Will AI replace designers? [4:13] Human vs. AI creativity [8:38] Applying AI to design [11:35] Startups vs. incumbents This conversation is part of our AI Revoluti…
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AI Revolution: Copilots and the Future of Knowledge Work with Microsoft's Kevin Scott
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Microsoft CTO Kevin Scott, in conversation with a16z's Bob Swan, explains how AI copilots are keeping developers longer in a flow state and why AI copilots more broadly could be the start of an industrial revolution for knowledge work. [0:59] Microsoft's approach to AI [6:15] The next Industrial Revolution [10:47] Developer productivity & flow stat…
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a16z Cofounder and General Partner Marc Andreessen and Endeavor CEO Ari Emanuel are interviewed by a16z General Partner Sriram Krishnan at the “Time to Build: LA” event during LA Week. The trio chat about the future of content distribution, the bull case for VR over AR, the end of corporate brands, and why there is (or isn’t) ever anything good to …
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LATW 2022: Building the Future of Games
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In this episode of a16z Live, David Banks, a former Riot Games executive who's now the co-founder and CEO of Elodie Games, and Timmu Tõke, the co-founder and CEO of Ready Player Me, a leading platform for cross game avatars, join a16z General Partner and games investor Jon Lai for a conversation about where they think the metaverse is going, and th…
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In this episode of a16z Live, Chris Power, the Founder and CEO of the precision parts manufacturing company, Hadrian, talks with a16z American Dynamism Partner Oliver Hsu, about why he decided to build his factories in LA, why software engineers shouldn't be afraid of manufacturing company jobs, and how a single mom and pop machinist shop can affec…
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LATW 2022: Building Better Marketplaces
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In this episode of a16z Live, Grant LaFontaine, the co-founder and CEO of the livestream shopping platform Whatnot, talks with a16z General Partner Connie Chan about building the company, his experience as the site's first person to go live, and why he prefers Los Angeles over San Francisco. What follows is a slightly edited version of that convers…
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To celebrate the L.A. community and the city's growth, a16z recently hosted, "Time to Build Los Angeles," an event where we invited L.A.-based investors, founders, and operators from across a diverse range of industries to talk about company building in L.A. In the first in our series of interviews, we invited Andrew Chen from a16z, Minnie Ingersol…
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Titan's Clayton Gardner on How the Fintech Market is Changing
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In this episode of a16z Live, we are joined by Titan Invest co-founder and co-CEO Clayton Gardner; a16z General Partner Anish Acharya; and a16z growth partner, Alex Immerman. The trio starts their conversation by diving into the difference between active and passive investment management and where Titan fits into that matrix. Building upon that fou…
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Ben Horowitz on How the Best Leaders Build Culture
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Ben Horowitz discusses the leadership styles of Intel’s Andy Grove and Apple’s Bill Campbell, how Okta won its market with culture, and how to look for and hire the talent you don’t have in an interview with David Weiden, founding partner at Khosla Ventures, at the Khosla Ventures CEO Summit. Read a transcript of the conversation here. 0:40: The ma…
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The Importance of Partnerships in the Great Unbundling
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The API economy and a Cambrian explosion of apps are transforming best-in-class tech from monolithic tools to a stack of 20 applications that work together. Amid this unbundling, partnerships have become a critical part of early go-to-market strategy that can lead to higher quality pipeline and accelerated sales. In this fireside chat, recorded at …
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Goldman Sachs' Stephanie Cohen on How the Firm's Approach to Technology Has Evolved
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a16z General Partner David Haber chats with his former colleague Stephanie Cohen, Goldman Sachs' Global Co-Head of Consumer and Wealth Management, about her journey from being an investment banker to running a global division, how Goldman Sachs stays relevant to different client audiences, and how fintech entrepreneurs can think about partnering wi…
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CISA Deputy Director Nitin Natarajan on What Cybersecurity Threats Keep Him Up At Night
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As the deputy director for the Cybersecurity and Infrastructure Security Agency (CISA), Nitin Natarajan spends most of his days worrying about everything from risk identification and mitigation, to educating young people and small businesses on their potential to be victims. In this fireside chat with Joel de la Garza, a16z operating partner for se…
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Building Towards American Dynamism with Chris Power, CEO of Hadrian
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Katherine Boyle, General Partner at a16z is joined by Hadrian founder and CEO Chris Power, Packy McCormick, founder of Not Boring, and a16z co-founder Marc Andreessen to discuss the opportunity to automate and upskill in the precision parts industry and shore up U.S. manufacturing with new technology.…
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Ken Griffin on Unfettered Conversations with A and Z
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An excerpt from a Clubhouse conversation, where Marc interviews Ken Griffin, CEO and founder of Citadel, on GameStop one year later and why the stock price hasn't crashed, as well as about his winning bid for the Constitution in the auction against ConstitutionDAO.Av Marc Andreessen, Ken Griffin, Alex Rampell
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a16z Bio + Health #20: How useful is real world data in medicine?
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What are you doing with real world data? [1:39] How valuable is real world data? [7:24] How and where do we need shared data infrastructure? [16:37] Can real world data be used for clinical decision support? [20:40] Are diagnostic companies becoming the data aggregator layer? [26:52] What will define the core competency of academic medical centers …
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a16z Bio + Health #19: Going B2C2B in Digital Health
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Who is your "B" and who is your "C"? [2:02] Why did they choose B2C2B? [6:36] How did they craft their enterprise story? [11:42] Does going B2C2B increase CAC (customer acquisition costs)? [16:56] Three things to build an enterprise story around [22:26] How did their choice of B2C2B impact investor conversations? [34:23] What mix of consumer vs. he…
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One on One with A and Z #12: What is the most misunderstood area of markets?
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This is an excerpt from the a16z Clubhouse show One on One with A and Z, where a16z cofounders Marc Andreessen and Ben Horowitz answer questions on tech trends, company building, and more. To catch full live episodes of the show, follow the a16z Club on Clubhouse.Av Marc Andreessen, Ben Horowitz
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Good Time Show: Performance with Purpose with Indra Nooyi
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Indra didn't plan her career -- and that was a good thing [2:15] The personal tradeoffs of professional success [4:24] Deciding between a job at GE and PepsiCo [7:27] Rising up the ranks of PepsiCo [12:13] Transitioning PepsiCo to healthier foods... and doing well by doing good [16:34] Management hack: writing letters to parents [19:04] "Performanc…
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One on One with A and Z #11: How much rare knowledge is there?
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This is an excerpt from the a16z Clubhouse show One on One with A and Z, where a16z cofounders Marc Andreessen and Ben Horowitz answer questions on tech trends, company building, and more. To catch full live episodes of the show, follow the a16z Club on Clubhouse.Av Ben Horowitz, Marc Andreessen
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Good Time Show: What It Takes to Survive with Lyft Founder John Zimmer
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The early days of Zimrides [2:08] Driving early virality [7:56] Competing with Uber [15:47] Why they took political stances [27:03] Managing through the pandemic [38:09] The future focus for Lyft -- autonomous vehicles and the end of car ownership [42:50] Follow the a16z Club to join conversations with tech founders, builders, and leaders live and …
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a16z Bio + Health #18: What will it take to cure diabetes?
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An overview of diabetes Type 1 and Type 2 [2:58] Thinking beyond Type 1 and Type 2 [6:58] New treatment options: stem cells, continuous glucose monitoring [14:19] What's the timeline on stem cell therapies? [17:15] Therapies for controlling, rather than curing, diabetes [23:52] The current technology challenges to treating diabetes [29:52] The chal…
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a16z Bio + Health #17: Proteomics and Product around a Technological Breakthrough
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Founding story of Nautilus [1:43] Why was the Nautilus approach to proteomics a breakthrough? [6:12] Why a startup instead of academic research? [9:57] How to pick a good cofounder (it's not that different from choosing a spouse) [15:32] Advice for academic founders: how to work with VCs [21:14] The tipping points of scale & the challenges of findi…
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One on One with A and Z #10: The Impact of System Design on Culture
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This is an excerpt from the a16z Clubhouse show One on One with A and Z, where a16z cofounders Marc Andreessen and Ben Horowitz answer questions on tech trends, company building, and more live . To catch full episodes of the show, follow the a16z Club on Clubhouse.Av Marc Andreessen, Ben Horowitz
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Capital Markets #1 with MSCI CEO Henry Fernandez: What goes into an index?
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The MSCI origin story [1:07] How does an index get constructed? [6:51] How do you keep an index accurate? [11:42] MSCI business model... how do they get paid? [16:27] MSCI, competition, and why not an open source index? [23:14] ESG and investment objectives [27:00] ESG disclosure frameworks and the role of government in ESG [32:50] Defining ESG [34…
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SPEAKERS: Aarthi Ramamurthy, international, Clubhouse Donnie Dinch, founder and CEO, Bitski Gabby Dizon, cofounder, Yield Guild Games Jarrod Dicker, operating partner, TCG Jesse Walden, founder, Variant Fund Jon Lai, principal, a16z Packy McCormick, founder, Not Boring Sriram Krishnan, general partner, a16z Twobadour, founder, Metapurse Justin “3LA…
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a16z Infra #6: The Cost of Cloud vs. Repatriation
58:32
58:32
Spill senere
Spill senere
Lister
Lik
Likt
58:32
This conversation centers on the arguments and findings of the a16z piece The Cost of Cloud, a Trillion Dollar Paradox. The Core Findings of The Cost of Cloud piece [5:22] Cloud is a significant part of COGS for public SaaS companies [8:38] Should you allocate engineers to reduce cloud cost or just focus on growth? [12:06] How much of a problem is …
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