Beste Ashley Koff Rd Llc podcaster (2024)

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Are You a Fast Metabolizer of Omega Fatty Acids? Lessons from a Legend 1:08:59

12d ago1:08:59

1:08:59

It’s not overstating it to say that I have cited Dr. Artemis Simopoulos’ work in virtually every lecture I have ever given that included the topic of omega-3 fatty acids. She is an incredible human being, indomitable NIH researcher, and absolute legend in her field. In our conversation on New Frontiers, Dr. Simopoulos reviews those essential truths…

1
A 360-Degree View of the Microbiome: Practical Strategies for Clinicians 1:07:00

1M ago1:07:00

1:07:00

The centrality of gut health in total body health and aging means it’s a key topic for us to keep revisiting and updating our knowledge on. For instance, how confident do you feel about interpreting analytical indices such as phyla distribution, dysbiosis index, diversity score, as well as the myriad bacterial populations that can be resident in th…

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Promise and Controversies: State of the State of Longevity Science with Matt Kaeberlein, PhD 1:25:09

2M ago1:25:09

1:25:09

It's important to me to include a variety of voices in the sphere of aging and longevity, and Matt Kaeberlein PhD is certainly one that I appreciate for his tempered and rational arguments. I value his insights and his work with other scientists who are tussling with the challenging questions and research interpretations in this field. We are at th…

1
Addressing the Gut-Skin Axis: A Root Cause Approach to Chronic Skin Conditions 1:07:05

2M ago1:07:05

1:07:05

In this episode of New Frontiers, Dr. Kara Fitzgerald sits down with Dr. Valerie Gershenhorn, a leading expert in functional dermatology and a Clinical Team Member for Diagnostic Solutions Laboratory, to explore the profound impact of the gut-skin axis and autonomic nervous system on chronic skin conditions like acne, eczema, and more. Dr. Gershenh…

1
You Are Only As Young As Your Immune System with Dr. Greg Fahy 1:01:59

3M ago1:01:59

1:01:59

Your thymus isn't talked about much, but this small organ in your upper chest is a key component of your immune system that is solely responsible for the essential "education" of the immune cells that protect your body from invaders. Through this action it also affects levels of inflammation (an immune-mediated process). It's also interesting to no…

1
Innovative Approaches to Cardiovascular Care: A Deep Dive with Dr. Mark Houston 54:29

3M ago54:29

54:29

Cardiovascular disease might be the leading cause of death, but after my conversation with Dr. Mark Houston, I'm more convinced than ever that we have the power to change that narrative. We delved into the power of diet and lifestyle changes, the essential role of nitric oxide and the impressive results of innovative supplements like Vascanox HP by…

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Latest Research Data on Diet & Other Interventions for Multiple Sclerosis with Dr. Terry Wahls 1:02:50

4M ago1:02:50

1:02:50

What a tour de force conversation with Dr. Terry Wahls, who is, with her groundbreaking research, changing both conventional and functional medicine's approach to multiple sclerosis and ultimately patient care. I'm very excited to see the findings of her ongoing clinical trials, which evaluate the use of several popular dietary patterns, using MRIs…

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Targeting Cellular Senescence for Healthier, More Youthful Skin With Dr. Alessandra Zonari 58:11

4M ago58:11

58:11

*Save the date! Join me and Dr. Alessandra Zonari for a free webinar on July 25th 2024 and get your questions answered on all things OS-01 peptide and biological aging. Register at https://www.drkarafitzgerald.com/webinars/ I'm thrilled to be joined by Dr. Alessandra Zonari to take a deep dive into a breakthrough in skincare science that has caught…

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Resolving Chronic Inflammation using SPMs: A Two-Phase Approach with Ashley Koff RD 59:10

5M ago59:10

59:10

Practitioners, if specialized pro-resolving lipid mediators (SPMs) aren't already on your radar, you'll be a convert by the end of this New Frontiers episode. In functional medicine, we excel at addressing inflammation through nutrition and lifestyle. However, brilliant researchers like Dr. Charles Serhan from Harvard have shown us that resolving i…

1
Towards Predicting Autism in Utero with Dr. Janine LaSalle 1:05:19

5M ago1:05:19

1:05:19

What if we could actually identify and even correct significant autism risk factors in utero, before a baby is born? This is the promise of the game-changing research of Dr. Janine LaSalle, epigeneticist extraordinaire from UC Davis. With autism rates continuing to increase at alarming rates (the latest data from the CDC, released in 2023, is 1 in …

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Challenging Food Reactions? Addressing the Gut Microbiome and More with Dr. Thomas Fabian 1:10:46

6M ago1:10:46

1:10:46

Addressing adverse food reactions goes way beyond simply cutting out the culprits, so I’m thrilled to have Dr. Tom Fabian join us again on New Frontiers to highlight the interventions that will move the needle for our patients. We explore the mechanisms through which specific strains can either exacerbate or alleviate both immune-mediated and non-i…

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Smart, Actionable Strategies for Childhood Resilience, with Dr. Elisa Song 1:08:20

6M ago1:08:20

1:08:20

Dr. Elisa Song is one of those clinicians that I could just keep talking to! She's a respected colleague and pioneer in pediatric functional medicine with so many practical tips for navigating childhood illness and health. Need to get your kiddo/patient through a blood draw they don't want to do? Or get your picky eater to take their supplement? Dr…

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Mitigating Muscle Loss from GLP-1 Agonists, with Dr. Anurag Singh 31:38

7M ago31:38

31:38

Even as we prioritize natural interventions in functional medicine, GLP-1 agonist drugs such as Wegovy and Ozempic offer sometimes life-changing support for those who have long struggled with resistant overweight/obesity and high blood sugar. However, there are side effects, including the risk of substantial muscle loss and sagging, aged skin ("Oze…

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Tackling Alzheimer's Disease Head On - the Inspiring Work of Dr. Heather Sandison 42:14

7M ago42:14

42:14

Dr. Sandison confesses that when she first heard Dr. Dale Bredesen talk about his work reversing cognitive decline and Alzheimer's disease she was skeptical. But when she started to apply the Bredesen principles in her clinical work and saw just how meaningful the improvements were to patients' symptoms and quality of life, as she puts it: "...how …

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Targeting Senescent Cells? Dose and Timing Matters - with Dr. Greg Kelly 1:16:16

8M ago1:16:16

1:16:16

Get ready for a deep dive into the world of cellular senescence and its implications for aging. Dr. Greg Kelly joins me on New Frontiers to explain the science behind targeting this Hallmark of Aging and share natural compounds and activities that target cellular senescence. I am particularly excited for you to hear his thoughts around dosing and c…

1
Barry Sears (of Zone Diet Fame) on Lifetime Metabolic Health and Sourcing Omega-3s 1:08:50

8M ago1:08:50

1:08:50

I'm excited to welcome Dr. Barry Sears, the renowned creator of the Zone Diet and a pillar in our field. Dr. Sears has not only authored bestsellers but has also made incredibly important contributions to clinical practice which we still rely on today: He is, for instance, the scientist who put the use of the AA:EPA ratio on the map. Dr. Sears prov…

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Unraveling PCOS and Fertility: Debunking Common Misconceptions with Dr. Tara Harding 1:01:32

9M ago1:01:32

1:01:32

Gear up for an enlightening dive with Dr. Tara Harding, a vanguard in the realm of women’s health and fertility. Renowned for her exceptional work as a family nurse practitioner and fertility coach, Dr. Harding brings a wealth of knowledge from her battle against infertility and medical gaslighting, all while breaking barriers and fostering a suppo…

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AI, Digital Twins, and the Future of Personalized Medicine Interventions with Dr. Nathan Price 1:33:09

9M ago1:33:09

1:33:09

Fellow clinicians, get ready for a mind-blowing conversation with Dr. Nathan Price, Chief Scientific Officer of Thorne HealthTech and author of The Age of Scientific Wellness. Imagine harnessing AI to predict outcomes of our functional interventions (diet, supplements, lifestyle) by implementing a “digital twin” model that is populated with all of …

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Decoding Aging: The Science Of Cellular Rejuventation With Dr. Vittorio Sebastiano 1:49:12

10M ago1:49:12

1:49:12

It was a career-defining (and perhaps life changing) moment when Dr. Vittorio Sebastiano, a reproductive biologist by training, realized that because we are able to create life, that same body of information could be harnessed to create youth - that is, radically reverse our biological aging process to a younger time point without losing cellular i…

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Advanced Metabolomics: Identifying the Metabolic Signature for Aging with Betsy Redmond 59:49

11M ago59:49

59:49

Aging itself stands as the paramount driver of disease. As functional practitioners, the question arises: How can we assess biological age to make precise corrections that foster both healthspan and lifespan? Enter the era of omics, where metabolomics emerges as an exceptional tool with transformative potential. I'm thrilled to welcome back Dr. Bet…

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Burnout in Healthcare: Causes, Consequences, and Solutions with Dr. Jonathan Prousky 1:06:17

11M ago1:06:17

1:06:17

Working in healthcare brings a unique set of challenges and stressors. But the truth is that any of us can get to burnout through challenging circumstances of work or study. And the consequences can range from severe to devastating. Burnout still hasn't been fully understood or recognized by the medical profession and other industries - there is st…

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Beyond Mitochondrial Health: Can Urolithin A Slow Down Aging? 53:53

12M ago53:53

53:53

When it comes to mitochondrial health, few nutrients have burst onto the bioenergetics stage with quite the impressive force as the postbiotic rock star Urolithin A (UA). On this New Frontiers episode Dr. Chris Rinsch, co-founder of Amazentis / Timeline, shares the incredible scientific journey of UA's discovery and subsequent unfolding of its many…

1
Resolving Osteoporosis and Optimizing Bone Health - A Tour de Force Update 1:10:49

1y ago1:10:49

1:10:49

Did you know that "bone-eating" osteoclast cells are derived from immune cell precursors and are stimulated by inflammation, just like other immune cells? Or that bone has its own glycocalyx whose health is essential to realize the benefits of exercise for bone? Folks, Dr. Keith McCormick is back on New Frontiers with ever-more juicy pearls like th…

1
Breast Health and Beyond: A Practitioner's Guide to Functional Testing 1:16:08

1y ago1:16:08

1:16:08

Over 270,000 new cases of breast cancer are diagnosed each year in the US. And while BRCA mutations often get the most press, there are other, potentially more critical factors we can address. Today, Dr. Ruth Hobson joins us to delve into the realm of breast health, shedding light on both modifiable and non-modifiable risk factors, and sharing real…

1
Have You Met Your Imprintome Yet? Here’s Why You Should 1:15:46

1y ago1:15:46

1:15:46

The epigenetic pioneer, Dr. Randy Jirtle, returns to New Frontiers to share his latest groundbreaking work. And I really do mean groundbreaking. Dr. Jirtle's work in mapping our "imprintome" is literally creating a brand new branch of scientific study that is expected to provide valuable insights and opportunities for epigenetially-targeted therapi…

1
From Complex to Accessible: Streamlining Functional Medicine Labs 48:15

1y ago48:15

48:15

If you're a clinician and finding yourself pressed for time in your practice, you're certainly not alone. A recent survey of over 9,000 US physicians revealed that more than half are experiencing burnout. Fortunately, the field of functional medicine is rapidly evolving, bringing tools that promise to streamline and improve accessibility in our pra…

1
The Role of Adrenal Function in Thyroid Health and Longevity with Dr. Izabella Wentz 55:57

1y ago55:57

55:57

Get ready for an enlightening conversation as I welcome Dr. Izabella Wentz, renowned Thyroid Pharmacist and an accomplished author, to New Frontiers. We’ll talk about her new book and dive into the often underappreciated and enigmatic connection between adrenal dysfunction and hypothyroidism, and how extreme stress can accelerate aging and impact i…

1
Mark Newman: Maximizing Hormone Health With The DUTCH Test 59:38

1y ago59:38

59:38

In this episode, I have the pleasure of interviewing Mark Newman, the president and founder of Precision Analytical, the company behind the revolutionary DUTCH test.Mark is a true pioneer in the field of hormone testing, and in our conversation, we delve into the latest developments in this rapidly evolving field. We discuss how the DUTCH test has …

1
Specialized Pro-Resolving Mediators: As Close to a Panpharmacon as We Can Get? 1:13:59

1y ago1:13:59

1:13:59

Harvard's award-winning Dr. Charles Serhan isn't just an expert on specialized pro-resolving lipid mediators (SPMs), he is the scientist who actually discovered them. His breakthroughs opened up a brand new field of research and clinical application with immense potential. After all, chronic, unresolved inflammation is a contributor or cause of so …

1
Mastering Cardiovascular Longevity: Glycocalyx & Biohacking for Optimal Heart Health 52:32

1+ y ago52:32

52:32

Vascular health is fundamentally essential to longevity and health span, and that’s why I’m thrilled to be welcoming Dr. Michael Twyman to New Frontiers. Trained as an invasive cardiologist, Dr. Twyman has made the shift to a more preventative approach, moving beyond traditional cath lab results to focus on the health of the 60,000 miles of blood v…

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Evidence-Based Diet for Health and Stress Resiliency through the Microbiome with Dr. Vincent Pedre 1:07:44

1+ y ago1:07:44

1:07:44

I’m so happy to be here with Dr. Vincent Pedre to dig into emerging science on the microbiome. Dr. Pedre shares extensive clinical pearls from his vast experience in functional gut health in an approachable and fun way as he drills down on possible causes of the challenging gut epidemic we clinicians see in the increasing numbers of IBS patients wa…

1
Measuring Metabolites of Dysbiosis and Gut Function to Create Targeted Interventions 56:10

1+ y ago56:10

56:10

As we gain insight into microbiome impact on our health, we need accurate tests that tell us not only what and how much is there, but also which metabolites, or post-biotics created that can have downstream effects. So today I’m thrilled to welcome the brilliant Dr. Erika Ebbel Angle, PhD, biochemist, CEO, and co-founder of Ixcela, to discuss their…

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Sergey Young's Tech Innovations for Longevity and Biological Age Reversal 1:01:33

1+ y ago1:01:33

1:01:33

Buckle up everybody, because this conversation is a big tour de force of where we are headed in regards to longevity and innovative technology within healthcare. I am joined by my friend, longevity investor and visionary, Sergey Young, to discuss his incredibly important mission of extending healthy lifespans of at least one billion people using te…

1
Disrupting Anti-Aging Skincare by Targeting Senescent Cells 48:07

1+ y ago48:07

48:07

Imagine accurately determining the status of your skin’s age to tell whether it is younger or older than your chronological age, and then use this technology to determine whether expensive anti-aging serums and creams are effective, or actually causing more harm than good. Amazing, right?This is precisely the technology Dr. Carolina Reis Oliveira a…

1
Advances in Curcumin Bioavailability for Improved Absorption in Patients 31:41

1+ y ago31:41

31:41

The therapeutic value of curcumin makes it a fabulous recommendation as both a foundational and medicinal supplement. And since finding a preparation that is bioavailable is key to efficacy, affordability, and patient compliance, I’m excited to have Dr. Sonia Malani (from Integrative Therapeutics) here to talk about the latest advances in curcumin …

1
Evaluating Hormonal Dysfunction and Infertility 54:41

1+ y ago54:41

54:41

If you’ve followed my show for some time, you’ve probably come across the wealth of conversations I’ve had with the team at Precision Analytical about their DUTCH hormone tests – this is an ever-evolving topic that continues to pique my interest as a clinician looking to level up my toolkit. In today’s show, I’m pleased to dive into some of my favo…

1
Optimize Women's Exercise According to Hormone Levels, with Dr. Stacy Sims 59:58

1+ y ago59:58

59:58

Today we are taking on a revolutionary and provocative topic that I suspect will be quite liberating for many of us women (and practitioners who work with women) – a deep dive into how to optimize exercise training and performance during pre-, peri-, and post-menopause. This topic is of great importance to me as a cyclist and, I have to say, there’…

1
Addressing Long-COVID: Data-Driven Learning for Practitioners and Patients 1:07:09

1+ y ago1:07:09

1:07:09

As we find ourselves entering this fourth year since the world was first gripped by COVID-19, on an individual and practice level many of us are still grappling with its post-viral after-effects (long COVID). Drs Patrick Hanaway and Kara Parker, as well as my long-time mentor and former IFM CEO Laurie Hofmann, join me on this podcast to share the i…

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The Role of NAD+ in Aging, Chronic Disease, and Epigenetics with Dr. Nichola Conlon 1:04:11

1+ y ago1:04:11

1:04:11

One fascinating and incredibly important molecule to pay attention to in the field of healthy longevity is nicotinamide adenine dinucleotide (NAD+). It’s literally in every cell and contributes to over 300 different reactions in the body as a coenzyme substrate. Dr. Nichola Conlon, PhD, is an expert on NAD+ and launched Nuchido Laboratories (who sp…

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Reframing Microbiome Support for Functionality with Dr. Heather Zwickey 52:52

1+ y ago52:52

52:52

I first met Dr. Heather Zwickey when she was my immunology professor in medical school and made sure to stay in touch with her ever since. Her command of the microbiome literature is frankly unparalleled – and I can always learn more from her and this podcast proves it. Join me in this New Frontiers conversation about the latest perspectives on the…

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Optimizing Mitochondrial Health with Urolithin A, with Dr. Anurag Singh 41:54

2y ago41:54

41:54

I always appreciate talking to companies who heavily invest their time and dollars into preclinical and clinical science. And Timeline Nutrition, sponsor of this episode, is doing just that with dramatic results. They have figured out how to make a bioidentical Urolithin A, which compelling research has shown positively influences our mitochondrial…

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Multiple Sclerosis Recovery Updates: A Conversation with Dr. Terry Wahls 50:22

2y ago50:22

50:22

Dr. Wahls’ dramatic recovery from progressive, debilitating multiple sclerosis (she was wheelchair-bound at one point and unable to sit upright) using functional medicine principles continues to astound those who learn about it. She kindly returns to New Frontiers in this episode to give us her latest updates and refinements in her approach to heal…

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Gut Healing in Aging & Disease: Microbiome and Diet in Intestinal Barrier Regeneration 1:07:06

2y ago1:07:06

1:07:06

If you’re a practitioner looking to level up your toolkit for regenerating the intestinal barrier and healing the gut, then this interview with Dr. Tom Fabian, PhD is exactly what you need. This fundamental piece of our functional medicine toolkit continues to progress, and today we’re zooming way out from just patching up the gut. Dr. Fabian and I…

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Polyphenols, Novel Probiotic Strains & Metabolic Health: Latest in Microbiome Science 39:29

2y ago39:29

39:29

How much do we really know about the microbiome? What does it take to identify new probiotic strains and their associated health benefits? When should we leverage precise single strains and when is it more effective to use synergistic blends?I am grateful to talk again with the brilliant scientist and incredibly courageous entrepreneur, Dr. Colleen…

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How to be your own Genetic Engineer, Save Money, and Live Longer, with Dr. Michael Roizen 1:01:33

2y ago1:01:33

1:01:33

Dr. Michael Roizen is an extraordinarily well-read, well-researched, and experienced physician in the field of longevity medicine. He dates his first interest in the field back to 1979 as head of an intensive care unit, when he recognized that patients who were biologically younger dramatically reduced their risk for post-operative disease and deat…

1
Building Resilience for Optimal Functioning with Dr. Stephen Sideroff 56:52

2y ago56:52

56:52

Why are we often resistant to tackling stress and preprogrammed thought patterns? It’s a curious phenomenon that occurs even in those of us who really know the central role these psychological factors play in health, disease, and even aging. That’s why I'm thrilled to interview resilience expert Dr. Stephen Sideroff. After all, a full 25% of the bi…

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SPONSORED | Hydrogen Sulfide in Health, Disease & Longevity with Dr. Tom Fabian 1:01:12

2y ago1:01:12

1:01:12

In this New Frontiers in Functional Medicine® podcast, Dr. Tom Fabian delivers a well-justified challenge to our current thinking and a chance to build a more nuanced approach that will improve patient results around the topic of hydrogen sulfide, a compound that we have typically thought of as the “problem child” behind certain difficult SIBO case…

1
What to Do When Autoimmune Patients Fail Standard Elimination Diets 1:17:10

2y ago1:17:10

1:17:10

Functional medicine providers are well versed in addressing the myriad manifestations of autoimmune disease, but while our success rates are remarkably high, we still aren’t always able to help everyone using current toolsets (labs, sophisticated elimination diets, gut protocols, and so on). Enter Mymee, a digital app and coaching platform that hel…

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SPONSORED | The Critical Role Telomeres Provide in Aging, Senescence, and Disease 59:03

2y ago59:03

59:03

It’s always a pleasure to tap into Dr. Raffaele’s brain, and in this podcast he doesn’t disappoint. In fact, his practical contextualization of where we are with anti-aging medicine might just be one of the smartest you’ve heard yet. What is truly remarkable about Dr. Raffaele is not just his grasp of the field both scientifically and clinically, b…

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Add Superfoods and Epinutrients to Any Diet Using Broths and Tonics 1:11:13

2y ago1:11:13

1:11:13

I am always excited to share new and practical ways to bring Younger You principles to your dinner table and/or clinical practice. And this podcast is especially exciting where Jill Sheppard Davenport and I dive into using broths and tonics as health-promoting and healing foods. Yes, these have been part of our natural medicine toolbox for eons, bu…

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