PSMA Conundrums & Triplet vs Doublet | PROSPECT Podcast part 1

GU Cast | Urology Podcast

Player FM - Internet Radio Done Right

12 subscribers

Lagt til three år siden

Innhold levert av Professor Declan Murphy & Dr Renu Eapen, Professor Declan Murphy, and Dr Renu Eapen. Alt podcastinnhold, inkludert episoder, grafikk og podcastbeskrivelser, lastes opp og leveres direkte av Professor Declan Murphy & Dr Renu Eapen, Professor Declan Murphy, and Dr Renu Eapen eller deres podcastplattformpartner. Hvis du tror at noen bruker det opphavsrettsbeskyttede verket ditt uten din tillatelse, kan du følge prosessen skissert her https://no.player.fm/legal.

Exile

1
Episode 10: From Refugee to Radical 44:09

for 2 years siden44:09

Spill senere

Lister

Lik

Likt

44:09

When a young Eva Kollisch arrives as a refugee in New York in 1940, she finds a community among socialists who share her values and idealism. She soon discovers ‘the cause’ isn’t as idyllic as it seems. Little does she know this is the beginning of a lifelong commitment to activism and her determination to create radical change in ways that include belonging, love and one's full self. In addition to Eva Kollisch’s memoirs Girl in Movement (2000) and The Ground Under My Feet (2014), LBI’s collections include an oral history interview with Eva conducted in 2014 and the papers of Eva’s mother, poet Margarete Kolllisch, which document Eva’s childhood experience on the Kindertransport. Learn more at www.lbi.org/kollisch . Exile is a production of the Leo Baeck Institute , New York | Berlin and Antica Productions . It’s narrated by Mandy Patinkin. Executive Producers include Katrina Onstad, Stuart Coxe, and Bernie Blum. Senior Producer is Debbie Pacheco. Associate Producers are Hailey Choi and Emily Morantz. Research and translation by Isabella Kempf. Sound design and audio mix by Philip Wilson, with help from Cameron McIver. Theme music by Oliver Wickham. Voice acting by Natalia Bushnik. Special thanks to the Kollisch family for the use of Eva’s two memoirs, “Girl in Movement” and “The Ground Under My Feet”, the Sophia Smith Collection at Smith College and their “Voices of Feminism Oral History Project”, and Soundtrack New York.…

for ca. et år siden 47:23

MP3•Episoder hjem

Highlights from a GU Cast Live Event! Dr Kim Chi (Medical Oncologist, Vancouver) and Dr Carmen Mir (Urologist, Valencia) joined the PROSPECT meeting in Melbourne to discuss high-risk prostate cancer and mHSPC, along with many experts from around Australia. On the eve of the meeting over dinner, Declan Murphy led a GU Cast-themed panel discussion on five hot topics in prostate cancer, featuring snippets from GU Cast over the past few months. Part 1 today features PSMA conundrums and triplet vs doublet therapy.
Even better on our YouTube channel
This is a Themed Podcast supported by our Gold Partners, Johnson & Johnson, who also support the PROSPECT meeting.
Special thanks to David Chen for help with videography

170 episoder

#Science #Fitness #Medicine #Dr Renu Eapen #Professor Declan Murphy #Urology #Prostate Cancer #Kidney Cancer #Testis Cancer #Penile Cancer #Gu Oncology #Cancer #Podcasting Education #Professor Declan Murphy And Dr Renu Eapen

PSMA Conundrums & Triplet vs Doublet | PROSPECT Podcast part 1

GU Cast | Urology Podcast

12 subscribers

published for ca. et år siden

Del

MP3•Episoder hjem

170 episoder

Alle episoder

GU Cast | Urology Podcast

1
Biochemical recurrence | With Steve Freedland 41:24

for 7 dager siden41:24

41:24

A fantastic episode for urologists, radiation oncologists, and anyone interested in localised prostate cancer. Biochemical recurrence (BCR) is unfortunately all too common after surgery or radiation for prostate cancer, and today we talk with someone who has been working in BCR for more than 20 years. Dr Steve Freedland, Urologist at Caesars-Sinai in Los Angeles, popped into the GU Cast studio to talk about the landmark series from Johns-Hopkins Medical Institute (links below) which still today remains our best guide to the natural history of BCR after radical prostatectomy. And the key message that PSA doubling time is our most important tool to risk stratify patients reminds true today. And Steve of course is the lead investigator of the EMBARK trial, published in NEJM in 2023, which has led to a new standard of care for men experiencing high-risk BCR after surgery or radiotherapy. EMBARK has clearly shown us that the use of enzaluamide, either on its own, or with androgen deprivation therapy, reduces the risk of metastases when compared with ADT alone. We dive deep into EMBARK with Steve. This is a Themed Podcast supported by our Gold Partners, Astellas. Astellas also supported Steve to be in Australia this week for the USANZ ASM in Perth, and visits to Melbourne and Sydney. Your hosts are Professor Declan Murphy and Dr Renu Eapen. Even better on our Youtube channel Links: Freedland et al JAMA 2005 EMBARK paper in NEJM…

GU Cast | Urology Podcast

1
Fellowship fun in Australia (and some prostate cancer chat)! 25:45

for 14 dager siden25:45

25:45

Two great international visitors recently led to two great sets of podcast chats!! Dr Kim Chi (Vancouver), and Dr Carmen Mir (Valencia) were in Melbourne to speak at the PROSPECT Meeting (see links below). We grabbed Kim along with Prof Arun Azad (Peter MacCallum Cancer Centre, Melbourne), and Dr Louise Kostos (also Peter Mac), to overlook some hot topics in mHSPC. And then a cracking chat with Carmen along with two Europeans doing Urology Fellowship training in Melbourne - Dr Christa Babst (Peter MacCallum Cancer Centre/Switzerland), and Dr Marta Alves (Royal Melbourne Hospital/Barcelona). Carmen had also done a Fellowship in Melbourne at Austin Health so could give some great perspectives. This is a Themed Podcast supported by our Gold Partners, Johnson & Johnson, who also supported the recent PROSPECT meeting. Even better on our YouTube channel Links: PROSPECT podcast Part 1 PROSPECT Podcast Part 2…

GU Cast | Urology Podcast

1
ENZA-P Big news Update: LuPSMA and enza improves overall survival 29:36

for 28 dager siden29:36

29:36

A breaking news podcast from ASCO GU in San Francisco! Prof Louise Emmett (St Vincent's, Sydney), has just read out the latest update from the ENZA-P trial (and simultaneous publication in Lancet Oncology), reporting that the combination of LuPSMA and enzalutamide improves overall survival when compared with enzalutamide alone, in men with poor prognosis mCRPC. Big news!! A 45% reduction in the risk of death in favour of the combination. Plus excellent quality of life for those receiving the combo. We are joined by Louise and co-author A/Prof Andrew Weickhardt (Austin Health, Melbourne), to discuss this exciting data from the ENZA-P trial, and what it means for the future of not just mCRPC, but also for similar combinations in mHSPC. ENZA-P is an investigator-initiated Phase II trial led by ANZUP in partnership with the Prostate Cancer Research Alliance, a join initiative between the Australian Government and Movember. Your co-hosts as ever are Professor Declan Murphy and Dr Renu Eapen. This is a Themed podcast supported by our Gold Partners, Astellas, and our Silver Partners, Novartis. Even better on our YouTube channel Links: Lancet Oncology paper ANZUP…

GU Cast | Urology Podcast

1
Future-gazing radioligand therapy in prostate cancer | With Oliver Sartor and Michael Hofman 37:27

for 6 weeks siden37:27

37:27

Look who popped into the GU Cast studio this week for a chat about where we are going next with radioligand therapy (RLT) for prostate cancer! Professors Oliver Sartor (Mayo Clinic, Rochester) and Michael Hofman (Peter Mac, Melbourne), are two of the world's most pre-eminent experts in the world of RLT for prostate cancer. They were each respectively PIs on the VISION and TheraP RCTs published in NEJM and Lancet in 2021, and both have many ongoing trials in RLT for prostate cancer. We hear in which stages of prostate cancer LuPSMA is next likely to be approved, and some discussion about exciting trials soon to read out. We also discuss other RLTs including actinium and terbium, combinations, imaging technology for patient selection, AI, and the word "cure" even gets a mention. A very entertaining and exciting discussion with two of the best in the business. Your regular hosts are Professor Declan Murphy and Dr Renu Eapen, Urologists at Peter MacCallum Cancer Centre, Melbourne. This is a Themed Podcast supported by our Silver Partners, Novartis. Even better on our YouTube channel Links: Michael's paper in the Journal of Nuclear Medicine :"The Hierarchy of SUVs: From Diagnostics to Therapeutics and the Pathway to Effective Theranostics"…

GU Cast | Urology Podcast

1
Toni's Legendary Top 10 Papers List! 48:48

for 8 weeks siden48:48

48:48

Dr Toni Choueiri, Chief of GU Oncology at Dana-Farber Cancer Institute (Boston, USA) returns to GU Cast with members of his team at Dana Farber Cancer Institute to discuss our favourite lists of top GU Oncology papers for 2024. Toni has posted these now legendary lists at the end of each year on Twitter/X since the start of Covid, and they have become essential reading for anyone wanting a superb overview of top trials. Each tweet contains a top line summary of each trial and key images such as K-M curves, plus links to the original papers. A huge amount of work and a great resource. Today we are joined by Toni along with Dr Marc Eid and Dr Emre Yekeduz who helped compile this year's lists. We hear about the process behind it all, and we run through their Top 10 Bladder and Renal Cancer papers, and their Top 5 Prostate Cancer papers. The team also post their Top 10 Translational papers and Their Top 10 non-GU Oncology papers. Well done again to Toni, Marc, Emre and team! Links to the tweets below. Even better on our YouTube channel Links: Top 10 Bladder and Renal Cancer Papers Top 5 Prostate Cancer Papers…

GU Cast | Urology Podcast

1
Shanghai GU Oncology Highlights Part 2 40:53

for 9 weeks siden40:53

40:53

Part 2 of our GU Cast Conference Highlights from Shanghai including discussions with Dr Stephen Freedland (Los Angeles), Dr Liang Liang (Shaanxi), Dr Andrea Necchi (Milano), Dr Xiaojie Bian (Shanghai), and Dr Hongkai Wang (Shanghai). Declan Murphy travelled to Shanghai for the 14th GU Oncology Academic Meeting hosted by Fudan University Shanghai Cancer Centre, and to meet up with our GU Cast China Editor, Dr Yao Zhu. This is an excellent meeting in one of our very favourite cities. In Part 1 we spoke to Conference Chair, Dr Dingwei Ye, Dr Karim Fizazi, Dr Peng Wu, and Dr Axel Merseburger, to overview the latest stories in GU Oncology. Special thanks to our Conference Highlights Partner, Bayer China, who set up an amazing GU Cast studio for us in Shanghai. Thanks to Hexun and all the local Bayer team in China. Also available as an audio podcast - just search GU Cast wherever you get your podcasts…

GU Cast | Urology Podcast

1
Shanghai GU Oncology Highlights Part 1 35:11

for 10 weeks siden35:11

35:11

Declan Murphy travels to Shanghai for the 14th GU Oncology Academic Meeting hosted by Fudan University Shanghai Cancer Centre, and to meet up with our GU Cast China Editor, Dr Yao Zhu. This is an excellent meeting in one of our very favourite cities, and this year Declan joins International Faculty including Dr Stephen Freedland (Los Angeles), Dr Karim Fizazi (Paris), Dr Axel Merseburger (Lubeck). and Dr Andrea Necchi (Milano) to overview the latest stories in GU Oncology. Top Chinese experts from across the country also join and the meeting includes some landmark consensus statements from multidisciplinary panels. Today we post Part 1 of our GU Cast Conference Highlights from Shanghai including discussions with Conference Chair, Dr Dingwei Ye, Dr Karim Fizazi, Dr Peng Wu, and Dr Axel Merseburger. Special thanks to our Conference Highlights Partner, Bayer China, who set up an amazing GU Cast studio for us in Shanghai. Thanks to Hexun and all the local Bayer team in China. Even better on our YouTube channel…

GU Cast | Urology Podcast

1
Stories of single-port surgery (and cricket) 33:58

for 11 weeks siden33:58

33:58

Our final episode of the year! And we end with a very seasonal celebration of single-port surgery and the Boxing Day Test with Australia playing India in one of the world's most famous cricket matches. We coaxed Dr Mihir Desai (University of Southern California, Los Angeles) and A/Prof Daniel Moon (Peter Mac, Melbourne) out of the Melbourne Cricket Ground and into our nearby studio at the close of play on Day 2 to talk all things single-port surgery (and cricket). Cricket-mad Mihir flew in from LA to tick off his bucket list ambition of attending a Boxing Day Test. We reminisce about the early days of single-port laparoscopy and talk about what robotic surgery does (and does not) bring to single-port surgery. Plus we remember the day that Indy Gill met Shane Warne at the MCG ten years ago while attending a meeting here! Two legends of their games. And to end season 5 of GU Cast, your hosts Declan Murphy and Renu Eapen thank our amazing Partners for supporting our ever expanding pool of content from GU Cast. Even better on our YouTube channel Links: BJUi Blog about when Indy met Warnie…

GU Cast | Urology Podcast

1
A Dummy's Guide to Metastatic Renal Cancer!! 37:49

for 14 weeks siden37:49

37:49

Have you ever found the choice of agents in metastatic kidney cancer just a bit perplexing??! Well then this is the podcast for you! To celebrate a fantastic review paper recently published in European Urology, we chat with first author Dr Regina Barragan-Carillo (City of Hope, California), and second senior author Dr Tian Zhang (UT South-Western, Texas). The title of the paper is "First and Second-line Treatments in Metastatic Renal Cell Carcinoma", and it's about the best paper we have read on this topic, with a proper who's who in renal cancer contributing. Plus completely up to date with a literature review up to October 2024. Co-hosts Declan Murphy and Renu Eapen really enjoyed this one! This is a Themed Podcast supported by our Bronze Partner, Ipsen Pharmaceuticals. Even better on our YouTube channel Links: European Urology paper (paywall)…

GU Cast | Urology Podcast

1
The Sir Chris Hoy Effect | Why family history matters 29:52

for 16 weeks siden29:52

29:52

Legendary British cyclist Sir Chris Hoy (48) recently shocked the world by announcing that he has progressive metastatic prostate cancer. His specialists have given him a 2-4 year life expectancy. The dreadful news that no prostate cancer patient wants to hear. Today, hosts Prof Declan Murphy and Dr Renu Eapen welcome their good mates A/Prof Ben Challacombe (Guy's Hospital, London), and A/Prof Daniel Moon (Peter MacCallum Cancer Centre, Melbourne) to the GU Cast studio, and patient advocate Andrei Norris who joins on Zoom to discuss the huge publicity this has generated, and the importance of family history in assessing men's risk of prostate cancer. This is a Themed Podcast supported by our Silver Partners, Bayer Pharmaceuticals. Even better on our YouTube channel…

GU Cast | Urology Podcast

1
PLND, ARPI Switch & De-Escalation | PROSPECT Podcast part 2 37:11

for 17 weeks siden37:11

37:11

Part 2 Highlights from a GU Cast Live Event! Dr Kim Chi (Medical Oncologist, Vancouver) and Dr Carmen Mir (Urologist, Valencia) joined the PROSPECT meeting in Melbourne to discuss high-risk prostate cancer and mHSPC, along with many experts from around Australia. On the eve of the meeting over dinner, Declan Murphy led a GU Cast-themed panel discussion on five hot topics in prostate cancer, featuring snippets from GU Cast over the past few months.Part 2 today features controversies in PLND, the somewhat notorious ARPI switch control arm beloved of mCRPC trials, and teh importnt topic of de-escalation in advanced prostate cancer. Part 1 recently in your feeds included PSMA conundrums and triplet vs doublet therapy. Even better on our YouTube channel This is a Themed Podcast supported by our Gold Partners, Johnson & Johnson, who also support the PROSPECT meeting. Special thanks to David Chen for help with videography…

GU Cast | Urology Podcast

1
The MSKCC PLND RCT | Please explain!!! 55:29

for 18 weeks siden55:29

55:29

What are we to make of this large RCT of extended vs standard pelvic lymph node dissection (PLND) for prostate cancer?? Despite it not meeting its primary endpoint of improving biochemical recurrence, the authors now report in European Urology that it does reduce the incidence of distant metastases 10 years later! Go figure! We chat with Dr Karim Touijer (MSKCC) and try to figure it out. We ask about data dredging, p-hacking and statistical shenanigans, and how adding two minutes and two extra lymph nodes to a PLND could possibly lead to reduced metastases. Plus guest comments from Dr John Yaxley (Brisbane). What do you think??!! Will this change practice?? Will this change guidelines? Tune in and share your thoughts! Even better on our YouTube channel Links: Paper in European Urology Previous GU Cast with Karim discussing earlier paper (Feb 2022)…

GU Cast | Urology Podcast

1
PSMA Conundrums & Triplet vs Doublet | PROSPECT Podcast part 1 47:23

for 19 weeks siden47:23

47:23

Highlights from a GU Cast Live Event! Dr Kim Chi (Medical Oncologist, Vancouver) and Dr Carmen Mir (Urologist, Valencia) joined the PROSPECT meeting in Melbourne to discuss high-risk prostate cancer and mHSPC, along with many experts from around Australia. On the eve of the meeting over dinner, Declan Murphy led a GU Cast-themed panel discussion on five hot topics in prostate cancer, featuring snippets from GU Cast over the past few months. Part 1 today features PSMA conundrums and triplet vs doublet therapy. Even better on our YouTube channel This is a Themed Podcast supported by our Gold Partners, Johnson & Johnson, who also support the PROSPECT meeting. Special thanks to David Chen for help with videography…

GU Cast | Urology Podcast

1
Treatment intensification in mHSPC | The Who, When, and How? Live webinar replay 1:32:38

for 19 weeks siden1:32:38

1:32:38

A GU Cast Live Event!! Everything you need to know about treatment intensification in mHSPC!! Doublet vs Triplet. Who should have radiotherapy? PSMA PET/CT conundrums, e-escalation, case discussions and more. Featuring GU Cast Hosts Declan Murphy and Renu Eapen, Medical Oncologist Ben Tran, Nuclear Medicine Physician Louise Emmett, and Radiation Oncologist Amy Hayden. Plus lots of interaction from our live audience around Australia. Watch the full webinar including presentations on our YouTube channel This GU Cast Live Event was an interactive educational webinar supported by our Gold Partners, Mundipharma. Learning objectives: 1. Provide an overview of the landscape of mHSPC today, with a particular focus on intensification of therapy 2. Provide an overview of the role of novel and conventional imaging in diagnosis of mHSPC, both synchronous and metachronous 3. To better understand options for intensification of systemic therapy in mHSPC 4. To better understand the role of radiotherapy in mHSPC…

GU Cast | Urology Podcast

1
ESMO24# Prostate Cancer Highlights | Reaction from China 45:39

for 21 weeks siden45:39

45:39

In the third of our special episodes focussing on GU Oncology in China, we are delighted to welcome back our GU Cast China Editor, Professor Yao Zhu, who has selected three huge prostate cancer highlights from the recent #ESMO24 meeting in Barcelona. We are joined by Professor Shouzhen Chen (Qilu Hospital, Shandong University), and Professor Zhenhua Liu (Sichuan University, West China Hospital) to discuss PEACE-3, ARANOTE, and UpFront PSMA, and in particular to consider what these data mean to health care professionals and patients in China. This is a Themed Podcast as part of our Gold Partnership with Bayer Pharmaceuticals in China. We are very grateful to Bayer China for helping us promote GU Cast in China and supporting these Themed Episodes. Even better on our YouTube channel You can also catch our recent full GU Cast Conference Highlights from #ESMO24 here…

Velkommen til Player FM!

Player FM scanner netter for høykvalitets podcaster som du kan nyte nå. Det er den beste podcastappen og fungerer på Android, iPhone og internett. Registrer deg for å synkronisere abonnement på flere enheter.